acc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T82019	JA-ACC	Jasmonyl-ACC
	Jasmonyl-ACC (JA-ACC), a derivative of 1-aminocyclopropane-1-carboxylic acid (ACC)—the direct precursor to ethylene—impedes root growth in Arabidopsis, with this effect being independent of jasmonic acid (JA) signaling [...
T3463	NVP-ACC789	ACC-789,ZK202650	VEGFR , PDGFR
	ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.		VEGFR , PDGFR
T7066	Fosphenytoin disodium	Fosphenytoin sodium,ACC-9653	Sodium Channel
	Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker		Sodium Channel
T4752	1-Aminocyclopropane-1-carboxylic acid	1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC	Endogenous Metabolite , NMDAR
	1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul...		Endogenous Metabolite , NMDAR
T27332	Flestolol sulfate	ACC 9089,ACC-9089,ACC9089
	Flestolol sulfate is an anti-adrenergic beta-receptor.
T27286	Esprolol hydrochloride	ACC9369,ACC 9369,ACC-9369
	Esprolol is a β-adrenergic receptor antagonist.
T80878	Vanutide cridificar	PF 05236806,ACC-001
	Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase
T7163	PF-05175157		Acetyl-CoA Carboxylase
	PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively		Acetyl-CoA Carboxylase
TQ0243	ND-646		Acetyl-CoA Carboxylase
	ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)		Acetyl-CoA Carboxylase
T3988	TOFA	MDL14514,RMI14514	Acetyl-CoA Carboxylase
	TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).		Acetyl-CoA Carboxylase
T14991	CMS-121	CMS121	Acetyl-CoA Carboxylase
	CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...		Acetyl-CoA Carboxylase
T1889	CP-640186	CP 640186	Acetyl-CoA Carboxylase
	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.		Acetyl-CoA Carboxylase
T5046	Haloxyfop	Haloxyfop Acid,(±)-Haloxyfop	Others , Acetyl-CoA Carboxylase
	(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.		Others , Acetyl-CoA Carboxylase
T3622	CP-640186 hydrochloride	CP 640186 HCl	Acetyl-CoA Carboxylase
	CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...		Acetyl-CoA Carboxylase
T7184	Firsocostat	ND-630,NDI-010976,GS-0976	Acetyl-CoA Carboxylase
	Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)		Acetyl-CoA Carboxylase
T3387	Phytolaccagenin		Others , Antibacterial
	Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae which are widely used in East Asian countries for the treatment of inflammation-related diseases.		Others , Antibacterial
T4330	CaCCinh-A01		Chloride channel
	CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).		Chloride channel
T41319	D-Saccharic acid 1,4-lactone hydrate		Others
	D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].		Others
T5132	9-dihydro-13-acetylbaccatin III	13-Acetyl-9-dihydrobaccatin III,9-DHAB III	Apoptosis
	9-dihydro-13-acetylbaccatin III (9-DHAB III)is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR.		Apoptosis