Home Tools
Log in
Cart

Fosphenytoin disodium

Catalog No. T7066   CAS 92134-98-0
Synonyms: Fosphenytoin sodium, ACC-9653

Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Fosphenytoin disodium Chemical Structure
Fosphenytoin disodium, CAS 92134-98-0
Pack Size Availability Price/USD Quantity
5 mg In stock $ 39.00
10 mg In stock $ 55.00
25 mg In stock $ 82.00
50 mg In stock $ 97.00
100 mg In stock $ 155.00
500 mg In stock $ 387.00
Bulk Inquiry
Get quote
Select Batch  
Purity: 99.91%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
In vivo Fosphenytoin has anticonvulsant activity in a mouse model of maximal electroshock seizures similar to that of phenytoin (ED50s = 16 and 8 mg/kg, respectively). It also has antiarrhythmic activity in isolated guinea pig atria and in anesthetized dogs. Formulations containing fosphenytoin have been used in the treatment of status epilepticus
Synonyms Fosphenytoin sodium, ACC-9653
Molecular Weight 406.24
Formula C16H13N2Na2O6P
CAS No. 92134-98-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 100 mg/mL (246.16 mM)

TargetMolReferences and Literature

1. Smith R D , Brown B S , Maher R W , et al. Pharmacology of ACC‐9653 (Phenytoin Prodrug)[J]. Epilepsia, 2010, 30(s2):S15-S21.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library FDA-Approved & Pharmacopeia Drug Library NO PAINS Compound Library Bioactive Compounds Library Max Ion Channel Inhibitor Library Anti-Cancer Compound Library Drug-induced Liver Injury (DILI) Compound Library FDA-Approved Drug Library

Related Products

Related compounds with same targets
Dibucaine hydrochloride Tocainide hydrochloride Sipatrigine Jingzhaotoxin XI Aah II Valproic Acid Propoxycaine hydrochloride Eslicarbazepine Acetate

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Fosphenytoin disodium 92134-98-0 Membrane transporter/Ion channel Sodium Channel inhibit Fosphenytoin sodium ACC 9653 ACC-9653 ACC9653 Fosphenytoin Inhibitor inhibitor

 

TargetMol