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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0010 | 6-Mercaptopurine | 6-MP,Mercaptopurine | Nucleoside Antimetabolite/Analog , Others , Dehydrogenase , Endogenous Metabolite , Autophagy |
6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with othe... | |||
T2201 | 6-Mercaptopurine hydrate | 6-Mercaptopurine monohydrate,6-Mercaptopurine (6-MP) Monohydrate | Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis |
6-Mercaptopurine hydrate (6-Mercaptopurine monohydrate) is a Nucleoside Metabolic Inhibitor. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs,... | |||
T26399 | 7-Methyl-6-mercaptopurine | 7-Methyl-6-thiopurine,6-Mercapto-7-methylpurine | Others |
7-Methyl-6-mercaptopurine (7-Methyl-6-thiopurine) is an inhibitor of PRPP aminotransferase, inhibits IMP metabolism and prevents purine, DNA and RNA synthesis. | |||
T7621 | 6-Thioinosine | 6-Mercaptopurine riboside,6TI | Nucleoside Antimetabolite/Analog |
6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent. | |||
T3089 | 6-Thioguanine | 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine | Apoptosis , DNA Methyltransferase , SARS-CoV , Endogenous Metabolite , DUB , Autophagy |
6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia. | |||
T1237 | Azathioprine | BW 57-322 | Apoptosis , GPR , Rho |
Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation. | |||
T40359 | Thio-ITP | 6-Thio-ITP,Thio-ITP,6-Mercaptopurine-riboside-5'-triphosphate,6-Thioinosine 5′-triphosphate | |
Thio-ITP, also known as 6-Thioinosine 5'-triphosphate, is a competitive inhibitor of RNA polymerase activity. It exhibits a strong apparent affinity towards the polymerases, with Ki values of 40.9 μM for RNA polymerase I... | |||
T69099 | Azathioprine Sodium | ||
Azathioprine Sodium is the sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substi... | |||
T36385 | Ansatrienin A | ||
Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM)... | |||
T36650 | Ansatrienin B | ||
Ansatrienin B is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis., In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 21 nM... |