Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00212 | CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc)
|
Human | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 b... | |||
TMPJ-00218 | SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated
SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a ... | |||
TMPJ-00233 | CD200R1/CRTR2 Protein, Human, Recombinant (His)
CD200R1/CRTR2 Protein, Human, Recombinant (His)
|
Human | Human Cells |
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and... | |||
TMPJ-00321 | LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated
LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | Human Cells |
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene co... | |||
TMPJ-00353 | ILDR2 Protein, Human, Recombinant (His)
ILDR2 Protein, Human, Recombinant (His)
|
Human | Human Cells |
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasi... | |||
TMPJ-00420 | CTLA-4 Protein, Mouse, Recombinant (Flag)
CTLA-4 Protein, Mouse, Recombinant (Flag)
|
Mouse | Human Cells |
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity w... | |||
TMPJ-00427 | LAIR1 Protein, Rhesus macaque, Recombinant (His)
LAIR1 Protein, Rhesus macaque, Recombinant (His)
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Rhesus Macaque | Human Cells |
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear c... | |||
TMPJ-00428 | PVRIG Protein, Mouse, Recombinant (hFc)
PVRIG Protein, Mouse, Recombinant (hFc)
|
Mouse | Human Cells |
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembr... | |||
TMPJ-00433 | VSIR Protein, Cynomolgus, Recombinant (His)
VSIR Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | Human Cells |
platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediat... | |||
TMPJ-00435 | PVRIG Protein, Cynomolgus, Recombinant (hFc)
PVRIG Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | Human Cells |
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembr... | |||
TMPJ-00436 | PVRIG Protein, Cynomolgus, Recombinant (His)
PVRIG Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | Human Cells |
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembr... | |||
TMPJ-00550 | Siglec-9 Protein, Human, Recombinant (hFc)
Siglec-9 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, f... | |||
TMPJ-00551 | Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
|
Human | Human Cells |
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, f... | |||
TMPJ-00555 | B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | Human Cells |
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C... | |||
TMPJ-00556 | B7-2 Protein, Human, Recombinant (His)
B7-2 Protein, Human, Recombinant (His)
|
Human | Human Cells |
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or C... | |||
TMPJ-00599 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
|
Human | Human Cells |
Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein ... | |||
TMPJ-00613 | CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus macaque | Human Cells |
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 b... | |||
TMPJ-00614 | CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
|
Rhesus Macaque | Human Cells |
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral mem... | |||
TMPJ-00624 | TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
|
Marmoset | Human Cells |
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of... | |||
TMPJ-00626 | CD160 Protein, Rhesus macaque, Recombinant (hFc)
CD160 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus macaque | Human Cells |
CD160 antigen is a cell membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in wh... |