Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00063 | CD160 Protein, Human, Recombinant (hFc)
CD160 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine... | |||
TMPJ-00107 | CTLA-4 Protein, Human, Recombinant (Flag)
CTLA-4 Protein, Human, Recombinant (Flag)
|
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 20 KDa and the accession numb... | |||
TMPJ-00108 | CTLA-4 Protein, Human, Recombinant (GST)
CTLA-4 Protein, Human, Recombinant (GST)
|
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (GST) is expressed in HEK293 mammalian cells with C-GST tag. The predicted molecular weight is 40-55 KDa and the accession num... | |||
TMPJ-00129 | BTLA Protein, Human, Recombinant (His)
BTLA Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induc... | |||
TMPJ-00173 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
|
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 ... | |||
TMPJ-00174 | TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
|
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-55 ... | |||
TMPJ-00175 | B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas,... | |||
TMPJ-00176 | B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellula... | |||
TMPJ-00179 | LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated
LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated
|
Human | HEK293 Cells |
LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weigh... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-... | |||
TMPJ-00182 | PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 70-95 KDa... | |||
TMPJ-00183 | PD-L1 Protein, Human, Recombinant (Flag)
PD-L1 Protein, Human, Recombinant (Flag)
|
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 35-40 KDa and the accession nu... | |||
TMPJ-00187 | CD300A Protein, Human, Recombinant (hFc & His)
CD300A Protein, Human, Recombinant (hFc & His)
|
Human | HEK293 Cells |
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of... | |||
TMPJ-00189 | TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)ex... | |||
TMPJ-00195 | FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
|
Cynomolgus | HEK293 Cells |
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 36... | |||
TMPJ-00197 | FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfami... | |||
TMPJ-00198 | FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | HEK293 Cells |
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 35 KDa ... | |||
TMPJ-00203 | Galectin-9 Protein, Human, Recombinant (GST)
Galectin-9 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galect... | |||
TMPJ-00208 | CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa ... | |||
TMPJ-00209 | CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
|
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 K... |