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Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag
Avi (34)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (95)
C-His-Avi (27)
C-hFc (87)
C-hFc-6xHis (2)
C-hFc-Avi (8)
C-mFc (16)
C-rFc (2)
His (60)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (31)
Cat No. product name / Synonyms Species Expression System
TMPY-05345 TIGIT Protein, Cynomolgus, Recombinant (hFc)
TIGIT Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
TIGIT Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.2 kDa and the accession nu...
TMPY-01342 CD73 Protein, Mouse, Recombinant (His)
CD73 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
CD73 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number i...
TMPY-05092 LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
Cynomolgus HEK293 Cells
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the acce...
TMPY-05079 PD-1 Protein, Human, Recombinant (mFc)
PD-1 Protein, Human, Recombinant (mFc)
Human HEK293 Cells
PD-1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.3 kDa and the accession number i...
TMPY-04342 PD-1 Protein, Canine, Recombinant (His)
PD-1 Protein, Canine, Recombinant (His)
Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number ...
TMPY-03377 CD73 Protein, Cynomolgus, Recombinant (His)
CD73 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
CD73 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession num...
TMPJ-00211 CD47 Protein, Human, Recombinant (His)
CD47 Protein, Human, Recombinant (His)
Human HEK293 Cells
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession num...
TMPY-01851 CD73 Protein, Human, Recombinant (His)
CD73 Protein, Human, Recombinant (His)
Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number i...
TMPY-03540 CD73 Protein, Rat, Recombinant (His)
CD73 Protein, Rat, Recombinant (His)
Rat HEK293 Cells
CD73 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is ...
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated
CD47 Protein, Human, Recombinant, Biotinylated
Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08...
TMPY-05579 PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
Human HEK293 Cells
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and t...
TMPY-05641 B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 49.8 k...
TIGIT Protein, Cynomolgus, Recombinant (hFc)
TMPY-05345
TIGIT Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.2 kDa and the accession nu...
CD73 Protein, Mouse, Recombinant (His)
TMPY-01342
CD73 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number i...
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
TMPY-05092
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the acce...
PD-1 Protein, Human, Recombinant (mFc)
TMPY-05079
PD-1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.3 kDa and the accession number i...
PD-1 Protein, Canine, Recombinant (His)
TMPY-04342
PD-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number ...
CD73 Protein, Cynomolgus, Recombinant (His)
TMPY-03377
CD73 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession num...
CD47 Protein, Human, Recombinant (His)
TMPJ-00211
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession num...
CD73 Protein, Human, Recombinant (His)
TMPY-01851
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number i...
CD73 Protein, Rat, Recombinant (His)
TMPY-03540
CD73 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is ...
CD47 Protein, Human, Recombinant, Biotinylated
TMPY-05191
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08...
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05579
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and t...
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05641
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 49.8 k...
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TargetMol