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Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag
Avi (34)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (95)
C-His-Avi (27)
C-hFc (87)
C-hFc-6xHis (2)
C-hFc-Avi (8)
C-mFc (16)
C-rFc (2)
His (60)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (31)
Cat No. product name / Synonyms Species Expression System
TMPJ-00627 CD160 Protein, Rhesus macaque, Recombinant (His)
CD160 Protein, Rhesus macaque, Recombinant (His)
Rhesus HEK293 Cells
CD160 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16-30 KDa and the acc...
TMPJ-00629 TIGIT Protein, Cynomolgus, Recombinant (His)
TIGIT Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT ...
TMPJ-00630 B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7-1 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
TMPJ-00632 B7-2 Protein, Cynomolgus, Recombinant (hFc)
B7-2 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession ...
TMPJ-00635 CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession...
TMPJ-00636 CTLA-4 Protein, Cynomolgus, Recombinant (His)
CTLA-4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the access...
TMPJ-00637 PD-L1 Protein, Cynomolgus, Recombinant (hFc)
PD-L1 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession num...
TMPJ-00638 PD-L1 Protein, Cynomolgus, Recombinant (His)
PD-L1 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accessi...
TMPJ-00640 CTLA-4 Protein, Cavia porcellus, Recombinant (His)
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
Cavia porcellus P. pastoris (Yeast)
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 ...
TMPJ-00641 B7-2 Protein, Rhesus macaque, Recombinant (His)
B7-2 Protein, Rhesus macaque, Recombinant (His)
Rhesus HEK293 Cells
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the acce...
TMPJ-00659 Galectin-9 Protein, Mouse, Recombinant (GST)
Galectin-9 Protein, Mouse, Recombinant (GST)
Mouse E. coli
Galectin-9 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 58 KDa and the accession...
TMPJ-00698 BTNL2 Protein, Mouse, Recombinant (His)
BTNL2 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I tran...
TMPJ-00949 CD96 Protein, Human, Recombinant (hFc)
CD96 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
CD96 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 110-160 KDa and the accession numb...
TMPJ-00950 CD96 Protein, Human, Recombinant (mFc)
CD96 Protein, Human, Recombinant (mFc)
Human HEK293 Cells
CD96 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 120 KDa and the accession number ...
TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His)
B7-1 Protein, Rabbit, Recombinant (His)
Rabbit HEK293 Cells
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ...
TMPJ-00959 B7-2 Protein, Rabbit, Recombinant (His)
B7-2 Protein, Rabbit, Recombinant (His)
Rabbit HEK293 Cells
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession nu...
TMPJ-01086 CD244 Protein, Mouse, Recombinant (His)
CD244 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins ha...
TMPJ-01199 BTN2A1 Protein, Human, Recombinant (His)
BTN2A1 Protein, Human, Recombinant (His)
Human HEK293 Cells
Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisi...
TMPJ-01242 CD160 Protein, Mouse, Recombinant (His)
CD160 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
CD160 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-25 KDa and the accession nu...
TMPJ-01246 BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293 Cells
BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 55-80 KD...
CD160 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00627
CD160 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16-30 KDa and the acc...
TIGIT Protein, Cynomolgus, Recombinant (His)
TMPJ-00629
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT ...
B7-1 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00630
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
B7-2 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00632
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession ...
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00635
CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession...
CTLA-4 Protein, Cynomolgus, Recombinant (His)
TMPJ-00636
CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the access...
PD-L1 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00637
PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession num...
PD-L1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00638
PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accessi...
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
TMPJ-00640
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 ...
B7-2 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00641
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the acce...
Galectin-9 Protein, Mouse, Recombinant (GST)
TMPJ-00659
Galectin-9 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 58 KDa and the accession...
BTNL2 Protein, Mouse, Recombinant (His)
TMPJ-00698
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I tran...
CD96 Protein, Human, Recombinant (hFc)
TMPJ-00949
CD96 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 110-160 KDa and the accession numb...
CD96 Protein, Human, Recombinant (mFc)
TMPJ-00950
CD96 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 120 KDa and the accession number ...
B7-1 Protein, Rabbit, Recombinant (His)
TMPJ-00958
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ...
B7-2 Protein, Rabbit, Recombinant (His)
TMPJ-00959
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession nu...
CD244 Protein, Mouse, Recombinant (His)
TMPJ-01086
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins ha...
BTN2A1 Protein, Human, Recombinant (His)
TMPJ-01199
Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisi...
CD160 Protein, Mouse, Recombinant (His)
TMPJ-01242
CD160 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-25 KDa and the accession nu...
BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-01246
BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 55-80 KD...
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TargetMol