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TargetMol | Compound Library

DNA Damage & Repair Compound Library

Catalog No. L3900

A significant barrier to effective cancer therapy is the development of resistance to the drugs utilized, therefore, identifying new biological targets and designing new drugs becomes one of the most important strategies. Among the various potential targets, DNA damage and repair system in cancer cells is one of the most pivotal targets. The use of unspecific antibiotics to treat bacterial infections has caused a great deal of multiple resistant strains making less effective the current therapies with antibiotics. Developing inhibitors of DNA repair and related pathways in pathogens will have utility in the treatment of infections.

The TargetMol's DNA Damage & Repair Compound Library, a unique collection of 1440 DNA Damage & Repair related compounds, can be used for research in DNA damage and repair, and high throughput screening (HTS) and high content screening (HCS).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3900

DNA Damage & Repair Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1440 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

DNA/RNA Synthesis
Apoptosis
PPAR
HDAC
Nucleoside Antimetabolite/Analog
PARP
Topoisomerase
Autophagy
Antibacterial
Endogenous Metabolite
Antibiotic
Sirtuin
DUB
NF-κB
Caspase
ROS
Parasite
PI3K
Virus Protease
DNA-PK
ATM/ATR
DNA Alkylator/Crosslinker
Akt
HIV Protease
mTOR
DHFR
Dehydrogenase
DNA
COX
Influenza Virus
Antifungal
Reactive Oxygen Species
AMPK
HSV
Bcl-2 Family
p38 MAPK
Wnt/beta-catenin
Interleukin
ERK
DNA Alkylation
Antifolate
SARS-CoV
STAT
Telomerase
MDM-2/p53
Antiviral
JNK
TNF
CDK
Mitophagy
DNA gyrase
HCV Protease
Ferroptosis
Cytochromes P450
ADC Cytotoxin
Nrf2
HBV
PKC
Prostaglandin Receptor
p53
Antioxidant
Adenosine Receptor
Mitochondrial Metabolism
IL Receptor
MMP
TGF-beta/Smad
Reverse Transcriptase
GABA Receptor
Potassium Channel
NO Synthase
PDE
Drug Metabolite
Calcium Channel
Antifection
Epigenetic Reader Domain
CRISPR/Cas9
Ras
Tyrosinase
JAK
Lipoxygenase
EGFR
HSP
AChR
Anti-infection
HIF/HIF Prolyl-Hydroxylase
PKA
Gamma-secretase
Pyroptosis
BMI-1
DNA Methyltransferase
Microtubule Associated
RAAS
Phosphatase
GSK-3
TRP/TRPV Channel
Bcr-Abl
MAPK
P-gp
TLR
transporter
MEK
Sodium Channel
GPCR
MicroRNA
Src
c-Myc
VEGFR
Adrenergic Receptor
MTH1
ABC Transporter
Glucosidase
Fatty Acid Synthase
IGF-1R
IκB/IKK
KLF
FLT
NOD-like Receptor (NLR)
Monoamine Oxidase
Proteasome
NOS
Carbonic Anhydrase
Histone Methyltransferase
Histone Demethylase
Glutathione Peroxidase
Tyrosine Kinases
Cell Cycle Arrest
Cysteine Protease
Leukotriene Receptor
Immunology/Inflammation related
LDL
Raf
Hedgehog/Smoothened
Angiotensin-converting Enzyme (ACE)
Aurora Kinase
glycosidase
CaMK
OXPHOS
LRRK2
cGAS
Casein Kinase
Beta Amyloid
ribosome
Phospholipase
Cannabinoid Receptor
Syk
FAK
Mdm2
ATPase
PROTACs
Transferase
NUDIX hydrolase
Integrin
Arginase
c-Met/HGFR
Reductase
IFNAR
NADPH
PERK
Histamine Receptor
Necroptosis
Serine/threonin kinase
FXR
IDO
IAP
FLAP
E1/E2/E3 Enzyme
PAFR
FABP
PAK
Cholinesterase (ChE)
Chk
Androgen Receptor
Indoleamine 2,3-Dioxygenase (IDO)
PGE Synthase
Free radical scavengers
Aminopeptidase
Histone Acetyltransferase
ALK
Methionine Adenosyltransferase (MAT)
Acetyl-CoA Carboxylase
Carboxypeptidase
Retinoid Receptor
PI4K
5-HT Receptor
PLK
NOD
S6 Kinase
HMG-CoA Reductase
Thrombin
Liposome
ROS Kinase
PD-1/PD-L1
Kras
Proton pump
Dopamine Receptor
Amino Acids and Derivatives
MyD88
Estrogen/progestogen Receptor
Ligands for Target Protein for PROTAC
YAP
P2Y Receptor
BACE
gp120/CD4
GTPase
OCT
Bcl-6
MRP
Estrogen Receptor/ERR
VDAC
Photosensitizer
Serine Protease
ATG
Glucokinase
ROCK
MAO
Aryl Hydrocarbon Receptor
iGluR
Prolyl Endopeptidase (PREP)
UGT
P2X Receptor
NMDAR
Monoamine Transporter
Molecular Glues
PDGFR
FAAH
CCR
PTEN
PAD
Xanthine Oxidase
Epoxide Hydrolase
cAMP
GluR
Orphan Receptor
Lipid
Beta-Secretase
Huntingtin
Survivin
STING
Trk receptor
GPCR19
Ephrin Receptor
CPT
RSV
c-Fms
Aromatase
PDK
Hydroxylase
Adenosine Deaminase
HIF
c-RET
SGK
Platelet aggregation
c-Kit
Sigma receptor
TAM Receptor
CFTR
MLK
HER
Drug-Linker Conjugates for ADC

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