Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 48.00 | |
10 mg | In stock | $ 77.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 193.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | 1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia. |
Source |
Synonyms | Rhynchophyllin, Rhyncophylline, Mitrinermine, Mitrinermin |
Molecular Weight | 384.47 |
Formula | C22H28N2O4 |
CAS No. | 76-66-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (65.02 mM)
You can also refer to dose conversion for different animals. More
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Rhynchophylline 76-66-4 Membrane transporter/Ion channel Metabolism NF-Κb NF-κB Calcium Channel inhibit Nuclear factor-κB Nuclear factor-kappaB Rhynchophyllin Inhibitor Rhyncophylline Mitrinermine Mitrinermin inhibitor