Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 101.00 | |
10 mg | In stock | $ 150.00 | |
25 mg | In stock | $ 312.00 | |
50 mg | In stock | $ 473.00 | |
100 mg | In stock | $ 693.00 | |
500 mg | In stock | $ 1,460.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 118.00 |
Description | NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response. |
Targets&IC50 | Fascin:2 μM |
In vitro | NP-G2-044 inhibits the migration of MDA-MB-231 tumor cells with an IC50?~10 μM. It decreases filopodial formation resulting in decreased lamellipodial formation[1]. |
In vivo | NP-G2-044 (100 mg/kg; i.p.; daily for 18 days) inhibits breast tumor metastasis in mouse models[1]. |
Molecular Weight | 399.37 |
Formula | C21H16F3N3O2 |
CAS No. | 1807454-59-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (250.39 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NP-G2-044 1807454-59-6 Others inhibit formation filopodial cell NPG2044 fascin filaments migration metastasis NP G2 044 actin NP-G-2-044 Inhibitor inhibitor