20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9247 | Vanilloid receptor antagonist 1 | 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile | TRP/TRPV Channel |
Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist. | |||
T1062 | Capsaicin | Qutenza,8-Methyl-N-vanillyl-trans-6-nonenamide,Vanilloid,(E)-Capsaicin,Zostrix | Apoptosis , TRP/TRPV Channel , Autophagy |
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities. | |||
T83701 | TRPV1-Tat TFA | Transient Receptor Potential Vanilloid 1-Tat,736-745-Tat | |
TRPV1-Tat, a peptide antagonist targeting transient receptor potential vanilloid 1 (TRPV1), is composed of amino acids 736-745 derived from TRPV1's A-kinase anchor protein (AKAP)-binding domain, combined with the HIV Tat... | |||
T6977 | SB-366791 | SB366791 | TRP/TRPV Channel |
SB-366791 is a new and selective cinnamide TRPV1 antagonist. | |||
T6848 | GSK1016790A | GSK101 | Calcium Channel , TRP/TRPV Channel |
GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells. | |||
T12306 | OMDM-5 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). | |||
T12302 | OMDM-1 | (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide | Endogenous Metabolite |
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. | |||
T23106 | Olvanil | N-Vanillyloleamide,N-Vannilyloleoylamide | TRP/TRPV Channel |
Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM. | |||
T23322 | SB 452533 | TRP/TRPV Channel | |
SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8). | |||
T29522 | ABT 102 | ABT102,CHEMBL398338,ABT-102 | TRP/TRPV Channel |
ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor. | |||
T13214L | TRPV4 agonist-1 free base | OUN67600 | TRP/TRPV Channel |
TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay). | |||
T14087 | ABT-239 | TRP/TRPV Channel | |
ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists. It also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist. | |||
T7189 | AMG9810 | TRP/TRPV Channel | |
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively). | |||
T37097 | SET 2 | TRP/TRPV Channel | |
SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4. | |||
TN1377 | α-Spinasterol | alpha-Spinasterol | COX , Antibacterial , TRP/TRPV Channel |
α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 v... | |||
T22360 | MDR-652 | TRP/TRPV Channel | |
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1 respectively and EC50s for hTRPV1 and rTRPV1 ... | |||
T2163 | Dihydrocapsaicin | CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide | Others , TRP/TRPV Channel |
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an... | |||
T22586 | Arvanil | Others | |
Cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist | |||
T23178 | PPAHV | Others | |
vanilloid TRPV1 (VR1) receptor agonist | |||
T22527 | 6'-Iodoresiniferatoxin | Others | |
TRPV1 (VR1) vanilloid receptor partial agonist |