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ABT 102

Catalog No. T29522 CAS 808756-71-0

Synonyms: ABT102, CHEMBL398338, ABT-102

ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

ABT 102, CAS 808756-71-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 437.00
10 mg	In stock	$ 646.00
25 mg	In stock	$ 987.00
50 mg	In stock	$ 1,380.00
100 mg	In stock	$ 1,860.00
500 mg	In stock	$ 3,720.00
1 mL * 10 mM (in DMSO)	In stock	$ 453.00

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Purity: 99.72%

ee: 99.58%

Purity: 99.17%

ee: 99.47%

Purity: 98.38%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.

Synonyms	ABT102, CHEMBL398338, ABT-102
Molecular Weight	348.44
Formula	C21H24N4O
CAS No.	808756-71-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (129.15 mM)

References and Literature

1. Jog R, et al. Formulation design and evaluation of amorphous ABT-102 nanoparticles. Int J Pharm. 2016 Feb 10;498(1-2):153-69. 2. Frank KJ, et al. What is the mechanism behind increased permeation rate of a poorly soluble drug from aqueous dispersions of an amorphous solid dispersion? J Pharm Sci. 2014 Jun;103(6):1779-86. 3. Leys LJ, et al. Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats. Pain. 2013 Jul;154(7):1092-102. 4. Frank KJ, et al. The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility. Int J Nanomedicine. 2012;7:5757-68.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library Inhibitor Library Bioactive Compounds Library Max Neuronal Signaling Compound Library Bioactive Compound Library Anti-Cancer Compound Library ReFRAME Related Library

Related Products

Related compounds with same targets

TRPC6-PAM-C20 Vanilloid receptor antagonist 1 HC-070 TRPV3 antagonist 74a RN9893 1,4-Cineole MSP3 JYL 1421

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ABT 102 808756-71-0 Membrane transporter/Ion channel TRP/TRPV Channel CHEMBL-398338 ABT102 CHEMBL398338 ABT-102 CHEMBL 398338 inhibitor inhibit

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