testicular — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0787	Butylhydroxyanisole	BHA,E320,Butylated hydroxyanisole	Antioxidant , Ferroptosis , Reactive Oxygen Species
	Butylhydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.		Antioxidant , Ferroptosis , Reactive Oxygen Species
T21714	BMS453	BMS 453,BMS-189453	Retinoid Receptor
	BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.		Retinoid Receptor
T19739	Simazine	Tafazine,Aquazine,Radocon,Herbex	Others
	Simazine (Tafazine) is a chlorotriazine herbicide and pesticide. Simazine may lead to testicular degeneration, neuroendocrine disruption, mammary cancer, and fetal developmental delays.		Others
T34268	Raxofelast	IRFI016,IRFI-016,IRFI 016
	Raxofelast (IRFI-016) is a hydrophilic, non-systemic, vitamin-like antioxidant that reduces ischemia-reperfusion injury in testis. Raxofelast is a good candidate compound for stopping oxidative stress after acute testicu...
T16116	MLN-4760		RAAS
	MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypept...		RAAS
T1167	Cyproterone acetate	Androcur,Cyproterone 17-O-acetate	Androgen Receptor
	Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. ...		Androgen Receptor
T11847L	Liarozole	R75251 dihydrochloride	P450 , Retinoid Receptor
	Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 1...		P450 , Retinoid Receptor
T0272	Nilutamide	RU23908	Androgen Receptor
	Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto...		Androgen Receptor
T71913	Bourgeonal
	Bourgeonal is an agonist of human testicular olfactory receptor hOR17-4. It increases cytosolic calcium levels in human spermatozoa, acts as a chemoattractant, and increases swimming speed in sperm chemotaxis assays in a...
T11847	Liarozole dihydrochloride	R75251 dihydrochloride	Others
	Liarozole dihydrochloride is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lya...		Others
T78296	IMAB027	ASP1650
	IMAB027 (ASP1650) is a specific monoclonal antibody targeting CLDN6 (Claudin 6), a membrane protein of tight junctions aberrantly overexpressed in multiple human cancers, notably in ovarian cancers. This compound exhibit...
T71142	Tebuconazole-d9
	Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-...
T83825	Trofinetide acetate	NNZ-2566
	Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig...