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Nilutamide

Catalog No. T0272   CAS 63612-50-0
Synonyms: RU23908

Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progestogen, or glucocorticoid receptors. Therefore, Nilutamide can block the action of androgens of testicular and adrenal origin that stimulate the growth of malignant and normal prostatic tissue. Prostate Y is mainly androgen-dependent and can be treat with chemical castration or surgical. So far, antiandrogen monotherapy has not consistently been certified to be equivalent to castration.

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Nilutamide Chemical Structure
Nilutamide, CAS 63612-50-0
Pack Size Availability Price/USD Quantity
100 mg In stock $ 39.00
200 mg In stock $ 55.00
500 mg In stock $ 91.00
1 mL * 10 mM (in DMSO) In stock $ 43.00
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Purity: 98.67%
Purity: 98.45%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progestogen, or glucocorticoid receptors. Therefore, Nilutamide can block the action of androgens of testicular and adrenal origin that stimulate the growth of malignant and normal prostatic tissue. Prostate Y is mainly androgen-dependent and can be treat with chemical castration or surgical. So far, antiandrogen monotherapy has not consistently been certified to be equivalent to castration.
Synonyms RU23908
Molecular Weight 317.22
Formula C12H10F3N3O4
CAS No. 63612-50-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 7.9 mg/mL(25 mM)

TargetMolReferences and Literature

1. Raynaud JP. Am J Clin Oncol. 1988;11 Suppl 2:S132-47.

TargetMolCitations

1. Du X, Yi X, Zou X, et al.PCDH1, a poor prognostic biomarker and potential target for pancreatic adenocarcinoma metastatic therapy.BMC Cancer.2023, 23(1): 1-17.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Active Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Bioactive Compounds Library Max Clinical Compound Library Orally Active Compound Library Endocrinology-Hormone Compound Library Anti-Prostate Cancer Compound Library

Related Products

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Darolutamide AR antagonist 1 Zanoterone RU 58841 Androgen receptor degrader-1 YK11 UT-34 MI-136

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Keywords

Nilutamide 63612-50-0 Endocrinology/Hormones Androgen Receptor inhibit prostate cancer Inhibitor anticancer Nilandron T-47D RU 23908 RU-23908 Schistosoma antischistosomal RU23908 Parasite inhibitor

 

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