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Tebuconazole-d9

Catalog No. T71142 CAS 1246818-83-6

Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per day) administered during gestation reduces testosterone levels and increases testicular levels of progesterone and 17α-hydroxyprogesterone in male rat fetuses. It has a feminizing effect on male pups and a virializing effect on female pups. When administered to rats gestationally through postnatal day 42, tebuconazole (20 and 60 mg/kg per day) leads to cell death of pyramidal cells in the CA3-4 region of the hippocampus and layer V of the cortex concomitant with impairment in learning......

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Tebuconazole-d9, CAS 1246818-83-6

Pack Size	Availability	Price/USD	Quantity
1 mg	35 days	$ 445.00
5 mg	35 days	$ 1,320.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	316.87
Formula	C16H13ClD9N3O
CAS No.	1246818-83-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tebuconazole-d9 1246818-83-6 Nilotinib N-oxide Nilotinib metabolite P36 BEJ866 BEJ 866 inhibitor inhibit

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