splenocytes — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12079	ML604440		Proteasome
	ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.		Proteasome
T6933	Peficitinib	ASP015K,JNJ-54781532	Tyrosine Kinases , JAK
	Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.		Tyrosine Kinases , JAK
T3386	Kaempferitrin	Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside	cell cycle arrest , Glucokinase , IGF-1R
	Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos...		cell cycle arrest , Glucokinase , IGF-1R
T76778	Risankizumab	Risankizumab rzaa,SKYRIZI,ABBV 066,BI-655066	IL Receptor
	Risankizumab (BI 655066) is a humanized IgG monoclonal antibody (Kd <10 pM) targeting the IL-23 p19 subunit. Risankizumab inhibits IL-17 production induced by human IL-23 in mouse splenocytes with an IC50 value of 2 pM.R...		IL Receptor
T6S2099	Geraniin		Antioxidant , TNF
	1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ...		Antioxidant , TNF
T32948	Lumin
	Lumin is a cyanine dye that enhances interleukin 12-dependent interferon gamma production by lipopolysaccharide-stimulated mouse splenocytes.
TN1666	Ganoderic acid LM2		Others
	Ganoderic acid LM2 exhibits potent enhancement of ConA-induced mice splenocytes proliferation in vitro.		Others
T38038	(-)-Rasfonin
	(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimot...
T72858	Maydispenoid B
	Maydispenoid B, a potent immunosuppressor, effectively inhibits the proliferation of murine splenocytes activated by anti-CD3/anti-CD28 monoclonal antibodies (mAbs) and lipopolysaccharide.
T36507	Tetrachlorohydroquinone
	Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of re...
TQ0032L	Rosiptor acetate	AQX-1125,AQX 1125,AQX1125,AQX-1125 acetate
	Rosiptor is a potent and selective SHIP1 activator. AQX-1125 inhibits Akt phosphorylation in SHIP1-proficient but not in SHIP1-deficient cells, reduces cytokine production in splenocytes, inhibits the activation of mast ...
T36986	Colletodiol
	Colletodiol is a fungal metabolite that has been found inD. grovesiiand has immunosuppressant and antiviral activities.1,2It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s = 12...
T35761	Carviolin
	Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes...
T38283	Tetracosanoyl-sulfatide	C24 3'-sulfo Galactosylceramide (d18:1/24:0)
	Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of ...
T36323	C8 Galactosylceramide (d18:1/8:0)	C8 Galactosylceramide (d18:1/8:0)
	C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells w...
T35450	α-GalCer analog 8	α-GalCer analog 8,α-Galactosylceramide analog 8
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-load...
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3...
T35639	Sulfatides (bovine) (sodium salt)
	Sulfatides are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system. They are produced from the combination of ceramide and UDP-galacto...
T38285	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))	Others
	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like...		Others