spin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23046	N-tert-butyl-α-Phenylnitrone	(Z)-N-benzylidene-2-Methylpropan-2-aMine oxide	ROS , COX
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge...		ROS , COX
T21495	Spinosyn A		Others
	Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides.		Others
T9076	Spinosad		Others
	Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa. It is a mixture of the macrocyclic lactones spinosyn A and spinosyn D, which act as agonists of insect nicotinic acetylcholinester...		Others
T60512	Haspin-IN-3		Haspin Kinase
	Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.		Haspin Kinase
T6S2227	Spinosin	Flavoayamenin	Others
	1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...		Others
T2103	Ispinesib	CK0238273,SB-715992	Apoptosis , Kinesin , KSP
	Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.		Apoptosis , Kinesin , KSP
T8455	Spinorphin		Opioid Receptor
	Spinorphin is a heptapeptide, and is a potent enkephalin-degrading enzymes inhibitor.		Opioid Receptor
TN1377	α-Spinasterol	alpha-Spinasterol	COX , Antibacterial , TRP/TRPV Channel
	α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 v...		COX , Antibacterial , TRP/TRPV Channel
T37298	Spinacine		Endogenous Metabolite
	Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens...		Endogenous Metabolite
T3S2325	Ardisiacrispin A	Saxifragifolin B,LTS-4,Deglucocyclamin	HSV
	Ardisiacrispin A (Deglucocyclamin) has cytotoxic activity toward HepG2 cancer cell with the GI(50) value of 1.56μM, it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and disassembling microtubule...		HSV
T5S2228	6‴-Feruloylspinosin	6'''-Feruloylspinosin	NF-κB
	6‴-Feruloylspinosin (6'''-Feruloylspinosin) may possess anti-inflammatory activity.		NF-κB
T35060	VinSpinIn	Vinnie's Spindlin Inhibitor,TD020824a
	VinSpinIn is a probe for the Spin family proteins.
T60477	Haspin-IN-1
	Haspin-IN-1 (compound 2a) is an inhibitor of haspin (haploid germ cell-specific nuclear protein kinase) with an IC50 of 119 nM. Haspin-IN-1 also inhibits CLK1, DYRK1A, and CDK9 with IC50 of 221 nM, 916.3 nM, and 406.8 nM...
TN1397	Ardisiacrispin B		Others
	Ardisiacrispin B displays cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death.		Others
T78002	Spinorphin TFA	LVV-hemorphin-4 TFA
	Spinorphin TFA acts as an inhibitor for multiple enkephalin-degrading enzymes, including aminopeptidase (aminopeptidase), dipeptidyl aminopeptidase III (dipeptidyl aminopeptidase III), angiotensin-converting enzyme (angi...
T126533	Spinacetin 3-gentiobioside
	Spinacetin 3-gentiobioside is a useful organic compound for research related to life sciences. The catalog number is T126533 and the CAS number is 101021-29-8.
TN5122	Taxuspine B		Others
	Taxuspine B is a natural product from the Japanese yew Taxus cuspidata Sieb. et Zucc.		Others
T36207	Methylspinazarin
	Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml).1 It is selective for COMT over tyrosine hydroxyl...
T28960	Thaspine HCl	Thaspine,Thaspine HCl, NSC 135784,NSC-135784,NSC135784
	Thaspine is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.
TN3256	7beta-Acetoxytaxuspine C		Others
	7beta-Acetoxytaxuspine C is a natural product from Taxus canadensis.		Others