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Search Results for " sphingosine "

20

Compounds

Cat No. Product Name Synonyms Targets
T78473 Sphingosine (d17:1) C17 Sphingosine
Sphingosine (d17:1) (C17 Sphingosine) is a 17-carbon sphingolipid found in human skin that can be phosphorylated by sphingomyelin kinase.Sphingosine C-17 can be used as an internal standard to perform spectroscopic analy...
T5891 D-ERYTHRO-SPHINGOSINE trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine Phosphatase , Endogenous Metabolite , PKC
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
T38685 C12-Sphingosine C12-Sphingosine
C12-Sphingosine is a short-chain homologue of Sphingosine. It effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells.
T83883 Biotin Sphingosine Biotinyl Sphingosine
Biotin sphingosine, a biotinylated derivative of sphingosine (d18:1), serves as a probe in assays for detecting the phosphorylation activity of sphingosine kinase 1 (SPHK1) and SPHK2 in cell lysates.
T24044 Erythro-sphingosine, (+)- L-Erythro-c18-sphingosine,L-Erythro-sphingosine
Erythro-sphingosine, (+)- is a cell-permeable and reversible inhibitor of protein kinase C (IC50: 12 µM) and enhances Src kinase activity.
T37954 Sphingosine (d20:1) Sphingosine (d20:1)
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, howe...
T37955 Sphingosine-1-phosphate (d16:1) Sphingosine-1-phosphate (d16:1)
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO...
T72100 D-erythro-Sphingosine hydrochloride Erythrosphingosine hydrochloride,trans-4-Sphingenine hydrochloride,erythro-C18-Sphingosine hydrochloride,Erythrosphingosine hydrochloride ; erythro-C18-Sphingosine hydrochloride ; trans-4-Sphingenine hydrochloride
D-erythro-Sphingosine hydrochloride, also known as Erythrosphingosine, serves as a specific TRPM3 activator and induces retinoblastoma protein dephosphorylation.
T38262 Sphingosine (d14:1)
Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fu...
T34693 Sphingosine phosphorylcholine
Sphingosine phosphorylcholine is a wound healing agent.
T21500 Sphingosine-1-phosphate S1P Endogenous Metabolite , S1P Receptor , LPL Receptor
Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, GPR12.Sphingosine-1-phosphate is an intracellular second messenger that mobilises Ca2+ as an extracellular ligand for G-protei...
T6085 PF-543 Sphingosine Kinase 1 Inhibitor II,PF 543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
T22917 L-threo-Sphingosine C-18 Others
L-threo-Sphingosine C-18 is a protein kinase C inhibitor.
T81700 NBD Sphingosine
NBD Sphingosine (NBD-Sph), a fluorochrome-tagged sphingosine, is utilized in fluorescence assays for sphingosine kinases [1] [2].
T40849 C20 Ceramide N-Arachidoyl-D-sphingosine Endogenous Metabolite
C20 Ceramide is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-like behavior.
T35803 C14 Ceramide (d18:1/14:0) Cer(d18:1/14:0),N-Myristoyl-D-sphingosine
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research.
T21260 Psychosine Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1) PKC
Psychosine (Galactosylsphingosine) is a PKC inhibitor, a substrate for the enzyme galactosylceramide cerebrosidase (GALC), and a potential biomarker of Krabbe's disease.Psychosine is highly cytotoxic and induces cell dea...
T37436 C12-Ceramide N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine
C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activi...
T8461 SKI V Apoptosis , PI3K , S1P Receptor
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity
T20827 C8-Ceramide N-Octanoyl-D-erythro-Sphingosine
C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides.

Compounds

Sphingosine (d17:1)
T78473
Synonym: C17 Sphingosine
Target:
D-ERYTHRO-SPHINGOSINE
T5891
Synonym: trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine
Target: Phosphatase, Endogenous Metabolite, PKC
C12-Sphingosine
T38685
Synonym: C12-Sphingosine
Target:
Biotin Sphingosine
T83883
Synonym: Biotinyl Sphingosine
Target:
Erythro-sphingosine, (+)-
T24044
Synonym: L-Erythro-c18-sphingosine,L-Erythro-sphingosine
Target:
Sphingosine (d20:1)
T37954
Synonym: Sphingosine (d20:1)
Target:
Sphingosine-1-phosphate (d16:1)
T37955
Synonym: Sphingosine-1-phosphate (d16:1)
Target:
D-erythro-Sphingosine hydrochloride
T72100
Synonym: Erythrosphingosine hydrochloride,trans-4-Sphingenine hydrochloride,erythro-C18-Sphingosine hydrochloride,Erythrosphingosine hydrochloride ; erythro-C18-Sphingosine hydrochloride ; trans-4-Sphingenine hydrochloride
Target:
Sphingosine (d14:1)
T38262
Synonym:
Target:
Sphingosine phosphorylcholine
T34693
Synonym:
Target:
Sphingosine-1-phosphate
T21500
Synonym: S1P
Target: Endogenous Metabolite, S1P Receptor, LPL Receptor
PF-543
T6085
Synonym: Sphingosine Kinase 1 Inhibitor II,PF 543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
L-threo-Sphingosine C-18
T22917
Synonym:
Target: Others
NBD Sphingosine
T81700
Synonym:
Target:
C20 Ceramide
T40849
Synonym: N-Arachidoyl-D-sphingosine
Target: Endogenous Metabolite
C14 Ceramide (d18:1/14:0)
T35803
Synonym: Cer(d18:1/14:0),N-Myristoyl-D-sphingosine
Target:
Psychosine
T21260
Synonym: Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1)
Target: PKC
C12-Ceramide
T37436
Synonym: N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine
Target:
SKI V
T8461
Synonym:
Target: Apoptosis, PI3K, S1P Receptor
C8-Ceramide
T20827
Synonym: N-Octanoyl-D-erythro-Sphingosine
Target:
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TargetMol