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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78473 | Sphingosine (d17:1) | C17 Sphingosine | |
Sphingosine (d17:1) (C17 Sphingosine) is a 17-carbon sphingolipid found in human skin that can be phosphorylated by sphingomyelin kinase.Sphingosine C-17 can be used as an internal standard to perform spectroscopic analy... | |||
T5891 | D-ERYTHRO-SPHINGOSINE | trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine | Phosphatase , Endogenous Metabolite , PKC |
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator | |||
T38685 | C12-Sphingosine | C12-Sphingosine | |
C12-Sphingosine is a short-chain homologue of Sphingosine. It effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells. | |||
T83883 | Biotin Sphingosine | Biotinyl Sphingosine | |
Biotin sphingosine, a biotinylated derivative of sphingosine (d18:1), serves as a probe in assays for detecting the phosphorylation activity of sphingosine kinase 1 (SPHK1) and SPHK2 in cell lysates. | |||
T24044 | Erythro-sphingosine, (+)- | L-Erythro-c18-sphingosine,L-Erythro-sphingosine | |
Erythro-sphingosine, (+)- is a cell-permeable and reversible inhibitor of protein kinase C (IC50: 12 µM) and enhances Src kinase activity. | |||
T37954 | Sphingosine (d20:1) | Sphingosine (d20:1) | |
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, howe... | |||
T37955 | Sphingosine-1-phosphate (d16:1) | Sphingosine-1-phosphate (d16:1) | |
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO... | |||
T72100 | D-erythro-Sphingosine hydrochloride | Erythrosphingosine hydrochloride,trans-4-Sphingenine hydrochloride,erythro-C18-Sphingosine hydrochloride,Erythrosphingosine hydrochloride ; erythro-C18-Sphingosine hydrochloride ; trans-4-Sphingenine hydrochloride | |
D-erythro-Sphingosine hydrochloride, also known as Erythrosphingosine, serves as a specific TRPM3 activator and induces retinoblastoma protein dephosphorylation. | |||
T38262 | Sphingosine (d14:1) | ||
Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fu... | |||
T34693 | Sphingosine phosphorylcholine | ||
Sphingosine phosphorylcholine is a wound healing agent. | |||
T21500 | Sphingosine-1-phosphate | S1P | Endogenous Metabolite , S1P Receptor , LPL Receptor |
Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, GPR12.Sphingosine-1-phosphate is an intracellular second messenger that mobilises Ca2+ as an extracellular ligand for G-protei... | |||
T6085 | PF-543 | Sphingosine Kinase 1 Inhibitor II,PF 543 | Apoptosis , S1P Receptor , Autophagy , LPL Receptor |
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM. | |||
T22917 | L-threo-Sphingosine C-18 | Others | |
L-threo-Sphingosine C-18 is a protein kinase C inhibitor. | |||
T81700 | NBD Sphingosine | ||
NBD Sphingosine (NBD-Sph), a fluorochrome-tagged sphingosine, is utilized in fluorescence assays for sphingosine kinases [1] [2]. | |||
T40849 | C20 Ceramide | N-Arachidoyl-D-sphingosine | Endogenous Metabolite |
C20 Ceramide is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-like behavior. | |||
T35803 | C14 Ceramide (d18:1/14:0) | Cer(d18:1/14:0),N-Myristoyl-D-sphingosine | |
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research. | |||
T21260 | Psychosine | Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1) | PKC |
Psychosine (Galactosylsphingosine) is a PKC inhibitor, a substrate for the enzyme galactosylceramide cerebrosidase (GALC), and a potential biomarker of Krabbe's disease.Psychosine is highly cytotoxic and induces cell dea... | |||
T37436 | C12-Ceramide | N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine | |
C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activi... | |||
T8461 | SKI V | Apoptosis , PI3K , S1P Receptor | |
SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM), induces apoptosis and has antitumor activity | |||
T20827 | C8-Ceramide | N-Octanoyl-D-erythro-Sphingosine | |
C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides. |