social — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11857	LIT-001		Oxytocin Receptor
	LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM.		Oxytocin Receptor
T1180	Blonanserin	AD-5423	Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor
	Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side effects such as extrapyramidal ...
T9317	TAK-041	NBI-1065846	GPR
	TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist.		GPR
T15022	CVT-10216		Dehydrogenase
	CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 μM). CVT-10216 can reduce excessive alcohol drinking...		Dehydrogenase
T23483	U 99194 maleate	U-99194A maleate,U-99194 maleate salt,U-99194 maleate	Dopamine Receptor
	U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.		Dopamine Receptor
T23444	TCS 1105	N-(4-fluorobenzyl)-2-(1H-indol-3-yl)-2-oxoacetamide	Others
	TCS 1105 is a GABAA benzodiazepine receptor (BZR) ligand. TCS 1105 blocks Sema3A induced axonal growth cones collapse. TCS 1105 reduces anxiety-like behavior and enhances offensive behavior and social dominance in mice.		Others
T22453	Venlafaxine	Wy 45030	Serotonin Transporter
	Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.		Serotonin Transporter
T25672	Lesopitron		5-HT Receptor
	Lesopitron is an anxiolytic with pre- and postsynaptic 5-HT1A agonist activity and is more effective than 5-HT1A agonists in rat social interaction and marmoset anxiety models. lesopitron counteracts benzodiazepine withd...		5-HT Receptor
T32191	Irdabisant	CEP-26401,CEP 26401,CEP26401	Histamine Receptor
	Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant ex...		Histamine Receptor
T37816	SB 243213
	SB 243213 is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. SB 243213 shows greater than a 100-fold selectivity over a wide range o...
T38192	Unifiram		Others
	Unifiram is a nootropic agent.1It increases acetylcholine (ACh) release in the rat cerebral cortexin vivoand induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the ra...		Others
T68683	Sertraline Free Base
	Sertraline Free Base is a Selective Serotonin Reuptake Inhibitor (SSRI). It can treat depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social ...
T76183	Corazonin
	Corazonin, a highly conserved neuropeptide hormone prevalent in insects, acts as a key regulator of caste identity and behavior in social insects. It is preferentially expressed in workers and/or foragers across various ...
T11856	LIT-001 free base		Others
	LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM).		Others
T40528	Oxytocin free acid	9-Deamidooxytocin
	Oxytocin free acid, also known as 9-Deamidooxytocin, is an analog of oxytocin where the glycinamide residue at position 9 has been substituted with a glycine residue. Oxytocin, a pleiotropic peptide hormone, has wide-ran...
T37920	7(Z),11(Z)-Heptacosadiene
	The mating and social behaviors of insects are largely orchestrated by a suite of volatile cuticular hydrocarbon pheromones. 7(Z),11(Z)-Heptacosadiene is the predominant female-specific courtship pheromone of the fruit f...
T82266	GPR139 agonist-2
	GPR139 agonist-2 (compound 20a), a potent GPR139 agonist with an EC50 of 24.7 nM, has demonstrated efficacy in rescuing social interaction deficits and alleviating cognitive deficits in murine schizophrenia models, indic...
TP1504	Urocortin III, mouse TFA (357952-10-4 free base)	Urocortin III, mouse TFA
	Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2. Urocortin III (Ucn3) is a known component of the behavioral stress response sys...
T76025	Urocortin III, mouse TFA
	Urocortin III, mouse TFA, a corticotropin-releasing factor (CRF)-related peptide, preferentially activates CRF-R2 [1], demonstrating its significant role in the behavioral stress response system as a component of Urocort...
T37114	SB 242084 dihydrochloride
	SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.IC50 value: 9.0(pKi) [1]Target: 5-HT2C antagonistin vitro: SB 242...