signal — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23355	Signal Enhancer Hikari		Others
	Signal enhancer for use in western blotting, dot blotting and ELISA		Others
TP2291	signal transducer and activator of transcription 6 fragment		Others
	The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.		Others
T38373	2-heptyl-3-hydroxy-4(1H)-Quinolone	2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal	Others
	2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...		Others
T83727	Tat-NTS Peptide TFA	Tat-Nuclear Translocation Signal Peptide
	Tat-NTS peptide, a cell-penetrating compound, comprises the HIV-1 Tat protein transduction domain fused with a 10-amino acid sequence (residues 228-237) from the repeat III domain of annexin A1, serving as a nuclear tran...
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.		ERK
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
TN1417	Azadirachtin		Apoptosis , Antifection
	Azadirachtin has antifungal activity, used as an insecticide.		Apoptosis , Antifection
T5358	Longdaysin		ERK , Casein Kinase , CDK
	Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 µM). It also can inhibit ERK2 (IC50: 52 µM).		ERK , Casein Kinase , CDK
T3856	Tenuifoliside A		ERK , Others
	Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.		ERK , Others
T10479	BAY885		ERK
	BAY885 is a new ERK5 inhibitor.		ERK
T14360	AX-15836		ERK
	AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).		ERK
TQ0005	KO-947		ERK
	KO-947 is a potent and specific inhibitor of ERK1/2 kinases.		ERK
T5184	ERK5-IN-1		ERK
	ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).		ERK
T3857	Magnolin	(+)-Magnolin	ERK
	Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.		ERK
T14894	CC-90003		ERK
	CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.		ERK
T6066	SCH772984		ERK , MEK
	SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.		ERK , MEK
T1956	FR 180204	FR180204	Apoptosis , ERK
	FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.		Apoptosis , ERK
T5535	ERK5-IN-2		ERK
	ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.		ERK
T4091	Temuterkib	LY3214996	ERK
	Temuterkib (LY3214996) is a potent and selective, orally available inhibitor of the extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity.		ERK
T6818	DEL-22379	DEL22379	Apoptosis , ERK
	DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.		Apoptosis , ERK