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Corynoxeine

Name: Corynoxeine
Brand: TargetMol
SKU: T6S0655
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6S0655Cas No. 630-94-4

1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.

Corynoxeine

🥰Excellent

Purity: 99.73%

Catalog No. T6S0655Cas No. 630-94-4

1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.

Pack Size	Price	Availability
1 mg	$40	In Stock
5 mg	$98	In Stock
10 mg	$179	In Stock
25 mg	$297	In Stock
50 mg	$453	In Stock
100 mg	$653	In Stock
500 mg	$1,350	In Stock

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Batch Information

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Purity:99.73%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.

Chemical Properties

Molecular Weight	382.45
Formula	C₂₂H₂₆N₂O₄
Cas No.	630-94-4
Smiles	CO\C=C(/[C@H]1C[C@@H]2N(CC[C@]22C(=O)Nc3ccccc23)C[C@@H]1C=C)C(=O)OC
Relative Density.	1.25 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (143.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6147 mL	13.0736 mL	26.1472 mL	130.7360 mL
5 mM	0.5229 mL	2.6147 mL	5.2294 mL	26.1472 mL
10 mM	0.2615 mL	1.3074 mL	2.6147 mL	13.0736 mL
20 mM	0.1307 mL	0.6537 mL	1.3074 mL	6.5368 mL
50 mM	0.0523 mL	0.2615 mL	0.5229 mL	2.6147 mL
100 mM	0.0261 mL	0.1307 mL	0.2615 mL	1.3074 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc