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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36949 | Niaprazine | 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff... | |||
T3563 | Lvguidingan | Others | |
Lvguidingan is an Anticonvulsant agent. | |||
T8887 | 2'MeO6MF | GABA Receptor | |
2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functional recovery and dampens the stroke-induced inflammatory response... | |||
T6464 | Detomidine hydrochloride | MPV-253 AII,Domosedan,Detomidine HCl | Adrenergic Receptor |
Detomidine hydrochloride (MPV-253 AII) produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors. | |||
T2S2109 | Skimmianine | beta-Fagarine,Skimmianin,Chloroxylonine,Skimmiamine | Others |
1. Skimmianine (Chloroxylonine) is a spasmolytic agent. 2. Skimmianine (Chloroxylonine) shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G. | |||
T7699 | AZD7325 | AZD-7325 | P450 , GABA Receptor |
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator. | |||
T14983 | Clomethiazole | Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | P450 , GABA Receptor |
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C... | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
T0205 | Brompheniramine maleate | Dimotane,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane | 5-HT Receptor , Histamine Receptor |
Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors. | |||
TN2865 | (E)-3,4,5-Trimethoxycinnamic acid | O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid | Others |
(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum. | |||
T23445 | Anxiolytic/nonsedative agent-1 | TCS 1205 | GABA Receptor |
Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α... | |||
T11506 | Guaiapate | Mg 5454,Klamar | Others |
Guaiapate has an antitussive and sedative effect. | |||
T30248 | AZD 3043 | AZD-3043,THRX 918661,AZD3043 | |
AZD 3043 is a propofol derivative which acts as a sedative-hypnotic agent. | |||
T31724 | Etoxybamide | Others | |
Etoxybamide is a drug candidate for sedative (hypnotic). | |||
T28887 | Suriclone | RP-31264,RP31264,RP 31264 | GABA Receptor |
Suriclone (RP 31264) is a selective cyclic pyrrolidone analog with sedative and anxiolytic activity, but not significant sedative effects.Suriclone shows its effects by modulating GABA-A receptors. | |||
T14314 | Apronal | Apronalide,Allylisopropylacetylurea | Others |
Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders. | |||
T83647 | (Z)-Tenilapine | Others | |
(Z)-Tenilapine is trans-Tenilapine, cis-Tenilapine has sedative activity. | |||
T28303 | Pazinaclone | A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000 | GABA Receptor |
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity. | |||
T0227 | Bromisoval | 2-Bromo-N-carbamoyl-3-methylbutanamide,Isobromyl,BRN 1773255,Bromovalerylurea,Bromaral | Others |
Bromisoval (Isobromyl) is a mild hypnotic and sedative with potential toxicity. | |||
T7521 | Azaphen | Pipofezin hydrochloride,Pipofezine hydrochloride,Azafen | 5-HT Receptor , Serotonin Transporter |
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity. |