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AZD 3043

Catalog No. T30248 CAS 579494-66-9

Synonyms: AZD-3043, THRX 918661, AZD3043

AZD 3043 is a propofol derivative which acts as a sedative-hypnotic agent.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

AZD 3043, CAS 579494-66-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 293.00
5 mg	In stock	$ 722.00
10 mg	In stock	$ 987.00
25 mg	In stock	$ 1,520.00
50 mg	In stock	$ 1,980.00

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Purity: 99.21%

Purity: 98.19%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

AZD 3043 is a propofol derivative which acts as a sedative-hypnotic agent.

Synonyms	AZD-3043, THRX 918661, AZD3043
Molecular Weight	351.44
Formula	C19H29NO5
CAS No.	579494-66-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Wang S, Liu Q, Li X, Zhao X, Qiu L, Lin J. Possible binding sites and interactions of propanidid and AZD3043 within the γ-aminobutyric acid type A receptor (GABA(A)R). J Biomol Struct Dyn. 2018 Nov;36(15):3926-3937. doi: 10.1080/07391102.2017.1403959. Epub 2017 Nov 29. PubMed PMID: 29125020. 2. Sear JW, Egan TD. David (Propofol Wannabes) Versus Goliath (Propofol): AZD-3043 Goes Up Against the Giant! Anesth Analg. 2015 Oct;121(4):849-51. doi: 10.1213/ANE.0000000000000904. PubMed PMID: 26378696. 3. Egan TD, Obara S, Jenkins TE, Jaw-Tsai SS, Amagasu S, Cook DR, Steffensen SC, Beattie DT. AZD-3043: a novel, metabolically labile sedative-hypnotic agent with rapid and predictable emergence from hypnosis. Anesthesiology. 2012 Jun;116(6):1267-77. doi: 10.1097/ALN.0b013e31825685a6. PubMed PMID: 22531340; PubMed Central PMCID: PMC4056591.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AZD 3043 579494-66-9 AZD-3043 THRX918661 THRX 918661 THRX-918661 AZD3043 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.