retention — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3126	Bethanechol chloride	(±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride	AChR
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab...		AChR
T6581	Methyclothiazide	Duretic,Enduron,Aquatensen	Others , Carbonic Anhydrase
	Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.		Others , Carbonic Anhydrase
T12478L	Pinacidil	S 1230,P 1134,S-1230,P-1134,P1134	Potassium Channel
	Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.		Potassium Channel
T18894	5(6)-CFDA	CFDA,5-(6)-Carboxyfluorescein diacetate	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activities, which is required to activate its fluorescence, and cell-m...		Others
TP1295	Angiotensin I (human, mouse, rat)	Angiotensin 1 Human	Others
	Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in...		Others
T0522	Diammonium Glycyrrhizinate	Glycyrrhizin	Dehydrogenase
	Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and ...		Dehydrogenase
T1050	Prazosin hydrochloride	Prazosin hydrochloride,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,Minipress	Potassium Channel , MRP , Adrenergic Receptor , ABC , Autophagy
	Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic ...
T1666	Fludrocortisone acetate	9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,9α-fluorocortisol acetate	Glucocorticoid Receptor , Autophagy
	Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-respon...		Glucocorticoid Receptor , Autophagy
T34107	Polythiazide	P2525,NSC-108161,NSC 108161,P-2525,NSC108161
	Polythiazide (NSC-108161, P-2525) is used to treat fluid retention (edema) caused by a variety of causes, including congestive heart failure, severe liver disease (cirrhosis), kidney disease, or steroid or hormonal medic...
T34601	Sekdel sequence	Ser-glu-lys-asp-glu-leu
	Sekdel sequence, as a signal, leads to retention of at least two proteins in the endoplasmic reticulum of animal cells.
T26180	Sdz 280 446	Sdz 280,446,Sdz 280-446
	Sdz 280 446 is one of the most active cyclopeptolide of many resistance-modifying agents in restoring rhodamine-123 retention within multidrug-resistant P388 cells.
T37410	9(R)-HETE
	9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE . At a concentration of 300 nM, 9(R)-HETE activates RXRγ-dependent transcription 1.5 fold relative to a control. Stereochemical assignment of the (R) enantiomer ...
T37411	9(S)-HETE
	9(S)-HETE is an enantiomer which makes up 50% of (±)9-HETE . There are no reports of 9(S)-HETE occurring as an enzymatic lipoxygenation product. Whereas 12(S)-HETE promotes adhesion of several cell lines to endothelial c...
T68714	Iobenguane I 131
	Iobenguane I 131 is a guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. MIB...
T37155	8(R)-HETE
	8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish. Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC reten...
T74555	EDA-DA
	EDA-DA, an N-terminally tagged dipeptide probe, serves as a labeling agent for bacterial Peptidoglycan (PG), a fundamental component of the cell walls in most bacteria crucial for cellular division, shape retention, and ...
T37158	8(S)-HETE
	8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0...
TP1227	β-Amyloid (12-28)	β-amyloid 12-28,Amyloid β-Protein (12-28)
	Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.
T16547	PK14105		Others
	PK14105 has been evaluated biologically as a potential radioligand for positron emission tomography (PET) studies targeting peripheral benzodiazepine binding sites (PBBS) receptors. When administered to rats with unilate...		Others
T80130	SDF-1α (human)		CXCR
	SDF-1α (human) serves as a chemotactic agent for mononuclear cells through its interaction with the CXCR4 receptor, facilitating critical biological processes such as stem cell homing, retention, survival, and proliferat...		CXCR