recurrent — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T26889	Borofalan(10B)	L-4-Boronophenylalanine	Others
	Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.		Others
T7697	BIX-01294		Histone Methyltransferase , Autophagy
	BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).		Histone Methyltransferase , Autophagy
T1163	Betamethasone valerate	Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq	Glucocorticoid Receptor
	Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.		Glucocorticoid Receptor
T1959	BIX-01294 trihydrochloride	BIX 01294	Histone Methyltransferase , Autophagy
	BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.		Histone Methyltransferase , Autophagy
T77416	Opicinumab	BIIB033	Others
	Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis.		Others
T2073	GSK2636771	GSK 2636771,GSK-2636771	PI3K
	GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and advanced malignant neoplasm.		PI3K
T35390	Magrolimab	Hu5F9-G4,Magrolimab (anti-CD47)	Others
	Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits its antitumor activity by blocking CD47 and binds primarily to the N-terminal pyroglutamate of CD47, and can be used in combination wi...		Others
T5231	2-Methylsuccinic acid	Pyrotartaric Acid,Methylbutanedioic acid	Others , Endogenous Metabolite
	2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical mea...		Others , Endogenous Metabolite
T0884	1-Docosanol	Behenic alcohol,Behenyl alcohol,n-Docosanol,Docosanol	Antifection , HSV
	1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex viru...		Antifection , HSV
T28778	Silperisone HCl	RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336
	Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi...
T4716	Pyrrole-2-carboxylic acid	2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite
	Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela...		Endogenous Metabolite
T16152	Betamethasone 17-benzoate		Kinesin
	Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).		Kinesin
T17930	EC1167		Others
	EC1169 is a targeted tubulysin conjugate that utilizes EC1167 as its linker. This compound shows promise in the treatment of recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].		Others
T76918	Barecetamab
	Barecetamab (ISU-104), a fully human anti-ErbB3 monoclonal antibody, is utilized in researching recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) [1].
T76789	Imalumab
	Imalumab (BAX69), a recombinant human IgG1 monoclonal antibody, specifically targets macrophage inhibitory factor (MIF). It is utilized in the research of ovarian carcinoma, recurrent malignant ascites, and cancer [1].
T76970	Tagitanlimab
	Tagitanlimab (HBM-9167), a humanized anti-PD-L1 antibody (IgG1κ type), selectively inhibits the PD-L1 and PD-1 interaction. It shows promise for investigation in recurrent or metastatic nasopharyngeal carcinoma (NPC) [1]...
T77815	EC1167 hydrochloride
	EC1167 hydrochloride serves as the linker for EC1169, a prostate-specific membrane antigen-targeting tubulysin conjugate. EC1169 hydrochloride demonstrates potential in treating recurrent metastatic, castration-resistant...
T77108	Olinvacimab
	Olinvacimab (TTAC-0001), a fully human anti-VEGFR2 monoclonal antibody, demonstrates antiangiogenic activity by inhibiting VEGF binding to KDR, with a dissociation constant (K d) of 0.23 nM. It is utilized in research fo...
T76997	Socazolimab
	Socazolimab (ZKAB001), an anti-PD-L1 monoclonal antibody, demonstrates enduring safety and efficacy in treating recurrent or metastatic cervical cancer. Additionally, it shows promise for treating small cell lung cancer,...
T76920	Bectumomab
	Bectumomab (IMMU-LL 2), a humanized IgG2a monoclonal antibody (mAb) against human CD22 (antigen), serves as an anti-lymphoma agent. It is utilized in imaging procedures when combined with technetium 99 (Tc99m LL2 Fab), a...