pyrimidine — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4809	Pyrimidine	Metadiazine	Others , Endogenous Metabolite
	Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...		Others , Endogenous Metabolite
T1696	2-(1-Piperazinyl)pyrimidine		Adrenergic Receptor
	2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug.		Adrenergic Receptor
T2075	Pyrazolo[1,5-a]pyrimidine 4h		Others
	Pyrazolo[1,5-a]pyrimidine 4h is a morpholine derivative that is a selective antagonist of the adenosine A2A receptor. It has been shown to be neuroprotective in animal models of Parkinson's disease and Huntington's chore...		Others
T50078	2-(pentylsulfanyl)pyrimidine-4,6-diol		GPR
	2-(pentylsulfanyl)pyrimidine-4,6-diol is a novel GRP84 agonist.		GPR
T7256	4-Chlorothieno[3,2-d]pyrimidine
	4-Chlorothieno[3,2-d]pyrimidine is a useful organic compound for research related to life sciences. The catalog number is T7256 and the CAS number is 16269-66-2.
T7451	2-Cyanopyrimidine	2-cyano-Pyrimidine	Cysteine Protease
	2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)		Cysteine Protease
T9366	Pyrazoloadenine	4-Aminopyrazolo[3,4-d]pyrimidine	ROS
	Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.		ROS
T8621	ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE		Others
	ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE used for preparation of pyrimidopyrimidines as protein kinase inhibitors.		Others
T4746	Purine	7H-Imidazo(4,5-d)pyrimidine	Others , Endogenous Metabolite
	Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...		Others , Endogenous Metabolite
T8613	1-Ethyl-6-aminouracil	6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE	Adenosine Receptor
	1-Ethyl-6-aminouracil (6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE) is an intermediate in the synthesis of a series of new substituted Xanthines which have high affinity and selectivity for the human adenosine A2B receptors.		Adenosine Receptor
T50079	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine		Others
	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine can be used in the development of new deoxycytidine kinase (dCK) inhibitors.		Others
TN7191	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine	5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Others
	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) is a marine derived natural products found in Echinodictyum sp.		Others
T9945	MNK8	3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione	STAT
	MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].		STAT
T5078	Orotic acid monohydrate	2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate	Others , Endogenous Metabolite
	Orotic acid monohydrate is an intermediate product in pyrimidine metabolism.		Others , Endogenous Metabolite
T24639	PIH	pyrimidine-indole hybrid
	PIH is a ciliogenesis inhibitor by microtubule destabilization that acts by antagonizing Hh signaling by repressing cilia biogenesis and disassembly of alpha-tubulin in its stabilized form.
T2476	INCB032304	4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine	Others
	INCB032304 is an important pharmaceutical intermediate. It can be used in the preparation of Ruxolitinib phosphate (I008849), a janus kinase inhibitor, and in the preparation of Barretinib.		Others
T16922	SPOP-IN-6b	2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide	Others
	SPOP-IN-6b is an effective inhibitor of speckle-type POZ protein (SPOP) with an IC50 of 3.58 μM and can be used in stuides about the treatment of renal cancer.		Others
T13017	STL127705	Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione	DNA-PK , Others
	STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor and inhibits Ku70/80-DNA interaction with IC50 of 3.5 μM. STL127705 inhibits the activation of Ku-dependent DNA-PKCS kinase with IC50 of 2.5 μM.		DNA-PK , Others
T67762	2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid		Others
	2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid belonging to the pyrimidine family, which has been shown to have anti-inflammatory, anticonvulsant and antitumor properties.		Others
T67877	2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid		Others
	2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid is commonly used to synthesize compounds with anticancer and antitumor properties.		Others