postoperative — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9833	Opiranserin hydrochloride		P2X Receptor , GlyT , 5-HT Receptor
	Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50...		P2X Receptor , GlyT , 5-HT Receptor
T1242	Alvimopan		Opioid Receptor
	Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid...		Opioid Receptor
T21412	Ketorolac	Toradol,Sprix,Acuvail,Macril,Acular	COX
	Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.		COX
T1780	Parecoxib	SC 69124,Vorth-P,Valus-P	COX
	Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.		COX
T3126	Bethanechol chloride	(±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride	AChR
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab...		AChR
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
T16399	Opiranserin		P2X Receptor , GlyT , 5-HT Receptor
	Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) an...		P2X Receptor , GlyT , 5-HT Receptor
T1406	Amantadine hydrochloride	1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor , Influenza Virus
	Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.		Dopamine Receptor , Influenza Virus
T28703	SC-75416	SC75416
	SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.
T68057	Doxpicomine		Others
	Doxpicomine has analgesic activity and can be used to treat postoperative pain.		Others
T8157	Centhaquin	PMZ-2010,Centhaquine	Others
	Centhaquin (Centhaquine)e is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock		Others
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T31759	Felbinac Trometamol	L141,Felbinac,L-141,L 141
	Felbinac Trometamol is an intravenous preparation used to treat severe postoperative pain.
T27079	CR-665 Acetate	FE200665,CR-665,JNJ-38488502,CR665,FE-200665,JNJ38488502
	CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain.
T71551	KAI-1678
	KAI-1678 is an inhibitor of epsilon protein kinase C (εPKC). KAI-1678 is effective in the treatment of postoperative pain following total hip or total knee replacement.
T80501	Myr-TAT-CBD3		Calcium Channel
	Myr-TAT-CBD3, a CRMP2-CaV2.2 interaction inhibitor, has been shown to significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity in a rat model of postoperative pain, making...		Calcium Channel
T71601	CU-2010
	CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a...
T68563	Piroxicam olamine
	Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmeno...
T73233	Ciramadol	WY 15705
	Ciramadol (WY 15705) is a potent, orally active analgesic with both narcotic agonist and antagonist properties, useful in postoperative pain treatment research.