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Search Results for " p38mapk "

9

Compounds

Cat No. Product Name Synonyms Targets
T12189 NBDHEX Apoptosis , Glutathione Peroxidase , Autophagy
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
T2S2382 3'-Hydroxypterostilbene 3'-HPT Apoptosis , Autophagy
3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b...
T2836 Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin MEK , PI3K , Endogenous Metabolite
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...
T4S2063 Tetrahydrocoptisine STYLOPINE ERK , p38 MAPK , NF-κB
1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...
T23774 Bauerenol NSC 147745,Baurenol
Bauerenol is a triterpenoid from Indian Suregada angustifolia. It also induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma cells.
T11048 DIPQUO Others
DIPQUO is an activator of bone marker alkaline phosphatase (ALP). DIPQUO promotes the differentiation of mouse and human osteoblasts by activating p38MAPK-β. The EC50 in C2C12 cells was 6.27 μM.
T71058 Doramapimod HCl
Doramapimod HCl is the salt form of Doramapimod, a member of the N-pyrazole-N'-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB -796 has entere...
T23617 Aclacinomycin Aclacinomycins,Siwenmycin
Aclacinomycin A is an anthracycline drug. It sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation. It is used in the treatment of cancer.
TN1211 2-Hydroxy-3-methylanthraquinone ERK , p38 MAPK , Caspase
2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.
TargetMol