Search Result

Search Results for " p10 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T72553	ARTD10/PARP10-IN-1		PARP
	ARTD10/PARP10-IN-1 is a potent PARP inhibitor of the mono-ADP ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly ADP-ribose polymerase-1 (ARTD1/PARP1), with potential anticancer and antitumour activit...		PARP
T73447	NP10679		P450 , HER , NMDAR , Histamine Receptor
	NP10679 is an orally available, selective, brain-penetrating, potent, and pH-sensitive N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit.NP10679 inhibits histamine H1, hERG channels, and CYP enzymes, a...		P450 , HER , NMDAR , Histamine Receptor
T2156	WP1066		Apoptosis , JAK , STAT
	WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra...		Apoptosis , JAK , STAT
T67932	PARP10-IN-3		PARP
	PARP10-IN-3 is a potent and selective mono-Adp-ribotransferase PARP10 inhibitor that inhibits human PARP10 (IC50:480 nM). PARP10-IN-3 also inhibited human PARP2 and human PARP15 with IC50 values of 1.7 μM.		PARP
T9777	THP104c		Mitochondrial Metabolism
	THP104c is an inhibitor of mitochondrial fission.		Mitochondrial Metabolism
T73007	PARP10-IN-2		PARP
	PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and PARP15, with IC50 values of 27 μM and 11 μM, respectively.		PARP
T60567	PARP10/15-IN-2
	PARP10/15-IN-2 (Compound 8h) is a dual inhibitor of PARP10 and PARP15 with IC 50 values of 0.15 μM and 0.37 μM, respectively. PARP10/15-IN-2 can enter cells and rescue cells from apoptosis [1].
T60309	PARP10/15-IN-3
	PARP10/15-IN-3 (Compound 8a) is a potent PARP10 and PARP15 dual inhibitor with IC 50 values of 0.14 μM and 0.40 μM against PARP10 and PARP15, respectively. PARP10/15-IN-3 can enter cells and rescue cells from apoptosis [...
T60495	PARP10/15-IN-1
	PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].
TP1416	Gp100 (25-33), human TFA (212370-40-6 free base)	Gp100 (25-33), human TFA
	Gp100 (25-33), human TFA is a 25-33 amino acid fragment of human melanoma antigen.Gp100 (25-33), human TFA is a 9-amino acid (AA) epitopes restricted by h-2db and recognized by T cells.
TP1727	Gp100 (25-33), human
	Gp100 (25-33), human is the amino acids 25-33 fragment of the human melanoma antigen. It is a 9-amino acid (AA) epitope restricted by H-2Db and recognized by the T cells.This is amino acids 25 to 33 fragment of human mel...
T83685	UFP101 TFA
	UFP101 is a synthetic peptide that functions as an antagonist of the nociceptin receptor, demonstrating high affinity with a Ki of 0.06 nM in CHO cells expressing the human receptor. It exhibits selectivity for the nocic...
T39569	Gp100 (25-33), mouse	Mgp100 (25-33),Gp100 (25-33), mouse
	Gp100 (25-33) corresponds to residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100), which is an enzyme responsible for pigment synthesis. This epitope fragment is found in both normal melanocytes and me...
TP2145	JTP10-△-R9 TFA		JNK
	JTP10-△-R9 TFA is a selective inhibitor of JNK2 peptide (IC50: 89 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.		JNK
TP1948	PBP10	PBP 10
	Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro...
TP2146	JTP10-△-TATi TFA		JNK
	JTP10-△-TATi TFA is a selective inhibitor of JNK2 peptide (IC50: 92 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.		JNK
T73361	RP101988
	RP101988, the principal active metabolite of Ozanimod, is a potent and selective agonist for sphingosine-1-phosphate receptor 1 (S1PR1), exhibiting half-maximal effective concentrations (EC50s) of 0.19 nM for S1PR1 and 3...
T73360	RP101442
	RP101442, the active metabolite of Ozanimod, is a selective and potent agonist of the sphingosine-1-phosphate receptor 1 (S1PR1), displaying EC50 values of 2.6 nM for S1PR1 and 171 nM for S1PR5.
T81279	RhB-PBP10 TFA
	RhB-PBP10 TFA, a Rhodamine B-labeled PBP10 TFA (FPR2 antagonist), selectively inhibits granule mobilization and oxygen radical secretion in FPRL1-induced neutrophils [1].
T74445	ZA3-Ep10
	ZA3-Ep10, a zwitterionic lipid, is utilized in the formulation of lipid nanoparticles for RNA delivery in vivo and non-viral CRISPR/Cas gene editing applications.
T80290	PP102
	PP102, an antimicrobial peptide, exhibits activity against gram-positive bacteria, including B. subtilis (MIC: 25 µM), S. aureus (MIC: 13.3 µM), S. lutea (MIC: 63 µM), and B. pumilus (MIC: 23 µM) [1].
T75811	PBP10 TFA
	PBP10, a cell-permeable and selective gelsolin-derived peptide, inhibits formyl peptide receptor 2 (FPR2) over FPR1 [1]. This 10-amino acid (AA) peptide features a rhodamine conjugation at its N terminus, exhibiting bact...
TP1574	Gp100 (619-627)	Gp100 619-627
	This is a HLA-A*0201 restricted epitope used in melanoma studies.
T72554	ARTD10/PARP10-IN-2
	ARTD10/PARP10-IN-2 is a potent, non-selective inhibitor of mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1, exhibiting IC50 values of 2.0 μM and 9.7 μM, respectively.
T32417	KP1019	FFC14A,KP 1019,indazolium trans-tetrachlorobis(1H-indazole)ruthenate-(III)
	KP1019 is now discontinued.
T27848	LP10	LP-10,LP 10
	LP10 is a reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 and a Potent type II inhibitor of Trypanosoma cruzi CYP51.
T78593	JP104		FAAH
	JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].		FAAH
T11210	EP1013	F1013	Caspase
	EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.		Caspase
T82743	CFP10 (71–85)
	CFP10 (71–85) is an immunologically active peptide that induces IFN-γ production and cytotoxic T lymphocyte (CTL) activity in CD4+ and CD8+ T cells from individuals with diverse MHC class II and I expression profiles.
TP1805	T7 Tag Peptide
	T7 Tag Peptide is a tagged protein that is specifically recognised by T7 tag tag antibodies and can be used in different immunoassays as well as affinity purification.

Compounds

Target: P450, HER, NMDAR, Histamine Receptor

WP1066

T2156

Synonym:

Target: Apoptosis, JAK, STAT

Target: Mitochondrial Metabolism

Gp100 (25-33), human TFA (212370-40-6 free base)

TP1416

Synonym: Gp100 (25-33), human TFA

Synonym: Mgp100 (25-33),Gp100 (25-33), mouse

Synonym: Gp100 619-627

Synonym: FFC14A,KP 1019,indazolium trans-tetrachlorobis(1H-indazole)ruthenate-(III)

Cat No.	Product Name	Synonyms	Targets
TN2358	Fructo-oligosaccharide DP10/GF9	Fructo-oligosaccharide DP10/GF9	Others
	Fructo-oligosaccharide DP10/GF9 is a compound classified as a fructooligosaccharide (FOS) with a degree of polymerization (DP) of 10. FOS consists of a chain of 9 fructose units connected by (2→1)-β-glycosidic bonds, wit...		Others

Natural Products

Fructo-oligosaccharide DP10/GF9

TN2358

Synonym: Fructo-oligosaccharide DP10/GF9

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01926	S100A10 Protein, Human, Recombinant (His)	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that...
TMPY-01825	RP105/CD180 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RP105/CD180 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69 kDa and the accession number is Q99467.
TMPK-01475	HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPY-06011	SARS-CoV-2 NSP10 Protein (His)	SARS-CoV-2	E. coli
	NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp...
TMPH-03649	HSP100 Protein, Trypanosoma cruzi, Recombinant (His & Myc)	Trypanosoma cruzi	E. coli
	N/A. HSP100 Protein, Trypanosoma cruzi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22.9 kDa and the accession number is O15885.
TMPK-01553	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPY-01666	RP105/CD180 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	RP105/CD180 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95 kDa and the accession number is Q62192.
TMPY-06012	SARS-CoV-2 NSP10 Protein	SARS-CoV-2	E. coli
	NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp...
TMPY-01667	RP105/CD180 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	RP105/CD180 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.4 kDa and the accession number is Q62192.
TMPK-01551	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPK-01540	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPK-01476	HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is in...
TMPY-03977	DAP10 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	HCST (Hematopoietic Cell Signal Transducer, also known as DAP1) is a Protein Coding gene. HCST belongs to the DAP10 family. It is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. Th...
TMPY-01854	DPP10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w...