muscarinic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T80183	Muscarinic toxin 7
	Muscarinic toxin 7 (MT7) is a peptide exhibiting selective, noncompetitive antagonistic activity at the muscarinic M1 receptor [1].
T80477	Muscarinic toxin 3	MT3	Adrenergic Receptor
	Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57 for α1B, 8.13 for α1D, 8.49 for α2A, <6.5 for α2B, and 7.29 ...		Adrenergic Receptor
T81893	M1/M4 muscarinic agonist 2
	Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].
T11078	Deschloroclozapine		Serotonin Transporter
	Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.		Serotonin Transporter
T4981	Anisotropine Methylbromide		Prostaglandin Receptor , AChR
	Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.		Prostaglandin Receptor , AChR
T1760	TBPB		AChR
	TBPB is an allosteric M1 mAChR agonist.		AChR
T11095L	DREADD agonist 21		5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
	DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).
T1281	Tropicamide	Ro 1-7683	AChR
	Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in ...		AChR
T7555	Piperidolate hydrochloride		AChR
	Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs).		AChR
T9419	Fesoterodine	(R) Fesoterodine	AChR
	Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).		AChR
T9694	Emraclidine	CVL-231	AChR
	Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.		AChR
T23116	Oxotremorine sesquifumarate		AChR
	Oxotremorine sesquifumarate is a muscarinic agonist.		AChR
T0962	L-Hyoscyamine	Daturine,Hyoscyamine	AChR
	L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as w...		AChR
T2390	Cevimeline hydrochloride hemihydrate		AChR
	Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.		AChR
T28827	Sofpironium bromide	BBI4000,BBI 4000,BBI-4000	Others , AChR
	Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.		Others , AChR
T8304	Anisodamine Hydrobromide	6-Hydroxyhyoscyamine	Adrenergic Receptor , AChR
	Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.		Adrenergic Receptor , AChR
T8196	Arborine	Arborin	Others , AChR
	Arborine (Arborin) is a larval growth inhibitor from glycoslnis pentaphylla.		Others , AChR
T6575	LY2119620		AChR
	LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.		AChR
T4979	Procyclidine hydrochloride	(±)-Procyclidine hydrochlorid	NMDAR , iGluR
	Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.		NMDAR , iGluR
T1475	Fesoterodine fumarate	Toviaz,SPM 907	AChR
	Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo...		AChR