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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8526 | Metformin | 1,1-Dimethylbiguanide | Mitophagy , AMPK , Autophagy |
Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm... | |||
T0740 | Metformin hydrochloride | Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride | Mitophagy , AMPK , Autophagy |
Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells including colon, pro... | |||
T73712 | Metformin-d6 hydrochloride | 1,1-Dimethylbiguanide-d6 hydrochloride | AMPK , Autophagy |
Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuterated form of Metformin that can be used to study Metformin metabolism in vivo, and is often used as an internal standard for Metformin.ccc_R08 can be use... | |||
T32758 | Linagliptin mixture with metformin | Jentadueto Xr,Linagliptin / metformin,Jentadueto | |
Linagliptin mixture with metformin is used for the treatment of type 2 diabetes. | |||
T70806 | Metformin icosapent | ||
Metformin icosapent is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. | |||
T71222 | Metformin glycinate | ||
Metformin glycinate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. | |||
T69405 | Metformin embonate | ||
Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. | |||
T69049 | Metformin orotate | ||
Metformin orotate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. | |||
T20028 | Janumet | Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate | |
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. | |||
TN2252 | Syrosingopine | Dopamine Receptor | |
Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor. | |||
T70804 | Itasetron hydrochloride monohydrate | ||
Itasetron hydrochloride monohydrate is a potent 5HT-3 receptor antagonist. | |||
T8929 | BC1618 | 2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]- | Mitophagy , Others , E1/E2/E3 Enzyme , AMPK |
BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and imp... | |||
T83971L | LCC-12 FA | Antiviral , Antibacterial | |
LCC-12 FA is a dimer composed of metformin that induces a decrease in the NAD(H) pool by targeting mitochondrial copper(ii).LCC-12 FA reduces inflammation in mouse models of bacterial and viral infections and may be used... | |||
T8532 | IM156 | OXPHOS | |
IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in anima... | |||
T0242 | Sitagliptin | MK0431 | Proteasome , DPP-4 , Autophagy |
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedion... | |||
T11570 | HL271 | AMPK | |
HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment. | |||
T35532 | Galegine hydrochloride | ||
Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This comp... | |||
T83866 | LCC-12 formate | ||
LCC-12, a derivative of the biguanide metformin, acts as a copper (II) chelator. It efficiently forms a monomeric bond with copper (II) and at 20 µM, it mitigates hydrogen peroxide-induced oxidation from NADH to NAD+. At... |