isoform — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76655	Prokineticin 2 Isoform 2 (human)
	Prokineticin 2 Isoform 2 (human), a hypothalamic neuropeptide, regulates thermoregulation and energy metabolism while decreasing food intake in rodents. This isoform is implicated in the study of metabolic syndrome (MetS...
TP2098	Echistatin	Echistatin, α1 isoform
	Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycopro...
T76064	Beta-defensin 103 isoform X1, pig
	Beta-defensin 103 isoform X1, pig, is an antimicrobial peptide prevalent in various organisms, playing a crucial role in the initial defense strategy of their innate immune system against pathogens [1].
T76064L	Beta-defensin 103 isoform X1, pig TFA
	Beta-defensin 103 isoform X1, pig TFA, is an antimicrobial peptide present in various living organisms, playing a crucial role in the initial defense of their innate immune system against pathogens [1].
T16129	MPI_5a		HDAC
	MPI_5a is an effective and selective inhibitor of HDAC6 (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms and it also inhibits acyl-tubulin accumulation in cells (IC50: 210 nM).		HDAC
T6704	TG 100713	TG100713	PI3K
	TG 100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.		PI3K
T12103	MR-L2		PDE
	MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).		PDE
T2S1797	Santalol		Antioxidant , Antifungal
	1. Santalol has good antibacterial, anti-oxidation and anti-tumor activities. 2. α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly. 3. α-Santalol shows a significant antifungal ef...		Antioxidant , Antifungal
TN1778	Isoformononetin		IL Receptor , Antifection
	Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estro...		IL Receptor , Antifection
T2256	CNX-1351		PI3K
	CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor.		PI3K
T3985	GDC-0326	GDC 0326,GDC0326	PI3K
	GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).		PI3K
T14090	AC-55649		Retinoid Receptor
	AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.		Retinoid Receptor
T8584	6-Phenyldihydropyrimidine-2,4(1h,3h)-dione	2,4(1H,3H)-Pyrimidinedione,dihydro-6-phenyl-	Others
	6-Phenyldihydropyrimidine-2,4(1h,3h)-dione targets the polypyrimidine tract-binding protein 1 isoform a (human)		Others
T22774L	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
T14089	AC-261066	AC 261066	Retinoid Receptor
	AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.		Retinoid Receptor
T5743	Gymnemagenin		Liver X Receptor
	Gymnemagenin is a potent and selective antagonist for the β isoform of LXR, it has antihyperglycemic activity.		Liver X Receptor
T35501	5,6-trans-Vitamin D3	5,6-trans-Colecalciferol,5,6-trans-Cholecalciferol,Cholecalciferol EP Impurity A	Vitamin
	5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol） is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.		Vitamin
T1999	Taselisib	RG-7604,GDC-0032	PI3K , Carbonic Anhydrase
	Taselisib (GDC-0032) is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity.		PI3K , Carbonic Anhydrase
T14947	CHDI-390576		HDAC
	CHDI-390576 is a CNS penetrant class IIa HDAC inhibitor (IC50s: 54 nM, 60 nM, 31 nM, 50 nM for class IIa HDAC4, HDAC5, HDAC7, HDAC9). It shows >500-fold selectivity over class I HDACs (1, 2, 3) and ~150-fold selectivity ...		HDAC
T2057	BVT 2733		Dehydrogenase
	BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.		Dehydrogenase