hyperactivity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0046	Bavisant	JNJ-31001074	Histamine Receptor
	Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.		Histamine Receptor
T10871	CP-809101 hydrochloride		5-HT Receptor
	CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).		5-HT Receptor
T2150	Guanfacine hydrochloride	Tenex,Intuniv,Guanfacine	Adrenergic Receptor
	Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.		Adrenergic Receptor
T12352L	Oxidopamine hydrobromide	6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide	Mitophagy , Dopamine Receptor , Autophagy
	Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.		Mitophagy , Dopamine Receptor , Autophagy
T12352	Oxidopamine hydrochloride	6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride	Mitophagy , Dopamine Receptor , Autophagy
	Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.		Mitophagy , Dopamine Receptor , Autophagy
T60201	CX717		GluR
	CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect. CX 717 can be used for the research of adult attention deficit hyperactivity disorder (ADHD) [1] [2].		GluR
T12054L	MK-0249 FA	MK-0249 FA(862309-06-6 Free base)	Histamine Receptor
	MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults.		Histamine Receptor
T13133	Tetrabenazine Metabolite	(-)-β-Dihydrotetrabenazine,(-)-β-HTBZ	Monoamine Transporter
	Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetraben...		Monoamine Transporter
T33816	Ordopidine	ACR-325,ACR 325,ACR325	Dopamine Receptor
	Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity. Ordopidine acts as a dopamine D2 receptor antagonist in vitro and...		Dopamine Receptor
T10226	Sofiniclin	ABT 894	Others
	Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).		Others
T61544	Edivoxetine hydrochloride
	Edivoxetine hydrochloride is a highly effective and specialized compound used primarily as a norepinephrine reuptake inhibitor (NERI), indicated for the treatment of depressive disorder and attention-deficit/hyperactivit...
T31604	Edivoxetine	LY-2216684,LY 2216684,LY2216684
	Edivoxetine( LY2216684) is a selective norepinephrine reuptake inhibitor being developed as a treatment for attention deficit hyperactivity disorder (ADHD) and antidepressants.
T34752	Samelisant dihydrochloride	SUVN-G3031,SUVN-G 3031,SUVN G3031,SUVN-G3031 HCl
	SUVN-G3031 is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating ...
T32224	Isopropamide	Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid
	Isopropamide (R5) is a long-acting anticholinergic drug. It is used to treat peptic ulcers and other gastrointestinal disorders involving excess gastric acid (gastrointestinal acidosis) and hyperactivity.
T14970	Cipralisant	GT-2331	Others
	Cipralisant is a selective histamine H3 receptor antagonist in vivo, and an agonist in vitro (pKi: 9.9 for histamine H3 receptor; Ki: 0.47 nM for rat histamine H3 receptor). It has the potential for the treatment of atte...		Others
T69595	Ispronicline hemigalactarate
	Ispronicline, also known as AZD3480; TC 1734; TC-0173, and RJR 1734, is a alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties. Ispronicline is potenti...
T79803	5-HT2C agonist-3 free base		5-HT Receptor
	5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-induced hyperactivity [1].		5-HT Receptor
T34192	Pumiliotoxin C	Decahydro-5-methyl-2-propylquinoline,5-Methyl-2-propyldecahydroquinoline
	Pumiliotoxins (PTXs), are one of several toxins found in the skin of poison dart frogs. There are three different types of this toxin: A, B and C, of which toxins A and B are more toxic than C. Pumiliotoxins interfere wi...
T79802	5-HT2C agonist-3		5-HT Receptor
	5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced hyperactivity [1].		5-HT Receptor
T79784	VU6004909
	VU6004909 is a positive allosteric modulator of the mGlu5 receptor (pEC50: 7.59), exhibiting antipsychotic-like effects. It has the capability to reverse MK801-induced cortical hyperactivity and cognitive deficits [1] [2...