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Search Results for " gout "

20

Compounds

Cat No. Product Name Synonyms Targets
T0692 Allopurinol Zyloric,Zyloprim,Lopurin ROS , Xanthine Oxidase
Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
T0773 Febuxostat TMX 67,TEI 6720 ROS , Xanthine Oxidase
Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor.
T6376 Allopurinol Sodium Allopurinol sodium salt,Sodium allopurinol ROS
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
TP2215 Agouti-related Protein (AGRP) (25-82), human Others
Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalam...
T76301 Agouti-related Protein (AGRP) (83-132) Amide (human)
Agouti-related Protein (AGRP) (83-132) Amide (human) is a segment derived from the agouti-related protein (AGRP), abundantly present in the hypothalamus' arcuate nucleus. It predominantly functions as an inverse agonist ...
T8567 Amflutizole Xanthine Oxidase
Amflutizole used for the treatment of gout, and is a Xanthine oxidase inhibitor
T0456 Cinchophen Cinconal COX
Cinchophen (Cinconal), an analgesic drug, is utilized in treating gout.
T32194 Irtemazole R60844,R-60844,R 60844 Others
Irtemazole (R 60844) is a novel uricosuric substance that is valuable in the treatment of hyperuricemia and gout.
T78984 Xanthine oxidase-IN-10 XO8 analog ROS
Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.
T20347 Deoxybenzoin 2-Phenylacetophenone,Benzyl phenyl ketone,NSC-131456,NSC131456,NSC 131456 Others
Deoxybenzoin (2-Phenylacetophenone) is used to target immune sensors and xanthine oxidase. It is used for the treatment of gout.
T79854 Lingdolinurad OAT
Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.
T3994 Verinurad RDEA3170 OAT
Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
T2397 Topiroxostat FYX-051 P450 , ROS , Xanthine Oxidase
Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.
T0435 Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,NSC 75925 COX
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
T3328 Angelic Acid 2-Methylisocrotonic acid,(Z)-2-Methylbut-2-enoic acid,cis-2-Methyl-2-butenoic acid Others
Angelic Acid ((Z)-2-Methylbut-2-enoic acid) is a monocarboxylic unsaturated organic acid. Angelic acid esters are the active components of herbal medicine used against a wide range of various health disturbances includin...
T0855 (R)-Naproxen COX
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis...
T6875 Lesinurad RDEA594 OAT
Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with seru...
T61048 Puliginurad YL-90148 OAT
Puliginurad (YL-90148) is a potent and selective inhibitor of urate transporter protein (URAT) with inhibitory effects on uric acid reabsorption.Puliginurad can be used for the prevention and treatment of hyperuricemia a...
T77517 URAT1 inhibitor 7 OAT
URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of 4.2 μM.URAT1 inhibitor 7 can be used to study hyperuricemi...
T4746 Purine 7H-Imidazo(4,5-d)pyrimidine Others , Endogenous Metabolite
Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...
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