eukaryotic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22774L	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
TP2247	eukaryotic translation initiation factor 3		Others
	Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated i...		Others
T22774	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ...		Others
T1742	4E1rcat		PERK , Autophagy
	4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.		PERK , Autophagy
T11375	GCN2iB		Others , Autophagy
	GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM.		Others , Autophagy
T14044	4E2RCat		PERK
	4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5 μM).		PERK
T11374	GCN2-IN-6		Others , PERK
	GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6 is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8...		Others , PERK
T21508	Anhydrotetracycline hydrochloride		Antibacterial , Antibiotic
	Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.		Antibacterial , Antibiotic
T2665	4EGI-1	4EGI 1	Apoptosis , PERK , Autophagy
	4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).		Apoptosis , PERK , Autophagy
T3207	Briciclib	ON 014185	CDK , PERK , Autophagy
	Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.		CDK , PERK , Autophagy
T11373	GCN2-IN-1	A-92	Others
	GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.		Others
T9149	2BAct	2B-Act,2B Act	PERK
	2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response		PERK
T5173	SBI-0640756	SBI 0640756,SBI-756	PERK , Autophagy
	SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.		PERK , Autophagy
TQ0131	Rocaglamide	Rocaglamide A,Roc-A	HSP , NF-κB , PERK
	Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.		HSP , NF-κB , PERK
T6512	G-418 disulfate	Geneticin,G418 Sulfate,Antibiotic G-418 sulfate,Geneticin sulfate	Antibacterial , Antibiotic
	G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation.		Antibacterial , Antibiotic
T28506	Rbin-2		Phosphatase
	Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study...		Phosphatase
T62461	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine		Others
	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine can be used to alter eukaryotic lifespan.		Others
T67945	WAY-620473		PARP
	WAY-620473 is a potent PARP-1 inhibitor with antitumor activity and alters eukaryotic lifespan.		PARP
T7450	1-Phenylpropane-1,2-dione	1-Phenyl-1,2-propanedione,Acetyl benzoyl	Others
	1-Phenylpropane-1,2-dione (Acetyl benzoyl) is a eukaryotic metabolite produced in plant metabolic reactions.		Others
TQ0137	A-484954	A 484954	CaMK , Parasite , Autophagy
	A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.		CaMK , Parasite , Autophagy