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Briciclib

Name: Briciclib
Brand: TargetMol
SKU: T3207
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3207Cas No. 865783-99-9

Alias ON 014185

Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells.

Briciclib

🥰Excellent

Purity: 99.84%

Catalog No. T3207Alias ON 014185Cas No. 865783-99-9

Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells.

Pack Size	Price	Availability
1 mg	$39	In Stock
2 mg	$52	In Stock
5 mg	$80	In Stock
10 mg	$128	In Stock
25 mg	$263	In Stock
50 mg	$396	In Stock
100 mg	$589	In Stock
500 mg	$1,280	In Stock
1 mL x 10 mM (in DMSO)	$89	In Stock

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Batch Information

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Purity:99.84%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Briciclib (ON 014185) is a small molecule that inhibits cyclin D1 accumulation in Y cells.
Synonyms	ON 014185

Chemical Properties

Molecular Weight	474.42
Formula	C₁₉H₂₃O₁₀PS
Cas No.	865783-99-9
Smiles	C(=C/S(CC1=CC(OP(=O)(O)O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (105.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1078 mL	10.5392 mL	21.0784 mL	105.3918 mL
5 mM	0.4216 mL	2.1078 mL	4.2157 mL	21.0784 mL
10 mM	0.2108 mL	1.0539 mL	2.1078 mL	10.5392 mL
20 mM	0.1054 mL	0.5270 mL	1.0539 mL	5.2696 mL
50 mM	0.0422 mL	0.2108 mL	0.4216 mL	2.1078 mL
100 mM	0.0211 mL	0.1054 mL	0.2108 mL	1.0539 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc