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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16698 | Pyronin Y | C.I. 45005,Pyronine G | Others |
Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA. | |||
T22698 | TLR3-IN-1 | CU CPT 4a | TLR |
TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell... | |||
T12516 | Polyinosinic-polycytidylic acid sodium | Poly(I:C) sodium | Apoptosis , Others , TLR |
Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MD... | |||
T23171 | Polyinosinic-polycytidylic acid | Poly(I:C) | TLR |
Polyinosinic-polycytidylic acid (Poly(I:C)) is a double-stranded RNA (dsRNA) and a TLR3 agonist. Polyinosinic-polycytidylic acid induces natural immunity in mammals. | |||
T9113 | Myristicin | Myristicine | IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase |
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ... | |||
T73994 | Nedosiran sodium | ||
Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme. | |||
T39802 | Nedosiran | DCR-PHXC | |
Nedosiran (DCR-PHXC) is a GalNAc-dsRNA conjugate designed for RNA interference (RNAi) targeting lactate dehydrogenase (LDH). It serves as a potential therapeutic option for patients with primary hyperoxaluria (PH) and en... | |||
T73674 | Poly (I:C):Kanamycin (1:1) | ||
Poly(I:C):Kanamycin (1:1) is a compound comprising an equal mixture of synthetic double-stranded RNA (dsRNA), specifically Poly(I:C), a Toll-like receptor 3 (TLR3) agonist, and kanamycin, a positively charged (poly-NH3) ... | |||
T38234 | HCoV-229E-IN-1 | ||
HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, demonstrating efficacy with an EC50 value of 0.65 μM in MTS cells and 0.6 μM in CPE cells[1]. |