cross-linking — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1564	Cisplatin	cis-Diaminodichloroplatinum,CDDP	DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy
	Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.
T19106	2-(Pyridyldithio)ethylamine hydrochloride	(S)-2-Pyridylthio Cysteamine Hydrochloride	Others
	2-(Pyridyldithio)ethylamine hydrochloride ((S)-2-Pyridylthio Cysteamine Hydrochloride) is a disulfide intercalating cross-linking reagent.		Others
T1224	Cefuroxime sodium	Anaptivan,Cefuroxime sodium salt,Biociclin	Antibacterial , Antibiotic
	Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime...		Antibacterial , Antibiotic
T0164	Oxaliplatin	L-OHP	DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
	Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop...		DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
T5022	Ceforanide		Antibacterial , Antibiotic
	Ceforanide is a second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering ...		Antibacterial , Antibiotic
T14298	Rimiducid		Apoptosis , Others , Fatty Acid Synthase
	Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-link...		Apoptosis , Others , Fatty Acid Synthase
T78362	Transglutaminase	TG
	Transglutaminase (TG) is a thiolase that induces intermolecular cross-linking of proteins, by catalysing the formation of isopeptide bonds between the γ-carboxamide group of glutamine residues and the primary ε-amine gro...
T35271	Yoshi-864	Yoshi864,Improsulfan HCl,NSC102627,Improsulfan hydrochloride
	Yoshi-864 alkylates and cross-links DNA, thereby inhibiting DNA replication. It is an alkyl sulfonate DNA cross-linking agent with potential anti-cancer activity.
T32206	Isodityrosine
	Isodityrosine is a new cross-linking amino acid from plant cell-wall glycoprotein.
T21306	Glyfosfin
	Glyfosfin is a DNA cross-linking agent and an alkylating agent with anticancer activity.
T41026	Biotin-LC-LC-NHS
	Biotin-LC-LC-NHS is a SMCC cross-linking reagent, which serves as a labeling agent for antibodies and small molecules, like Paclitaxel.
T16890	SJG-136	NSC-694501	Others
	SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).		Others
T19944	DSSeb Crosslinker	DSSeb Cross linker,DSSeb Cross-linker
	DSSeb Crosslinker is a homobifunctional cross-linking reagent. It is useful in protein crosslinking and making antibody-drug conjugates.
T38765	UBE2T/FANCL-IN-1	UBE2T/FANCL-IN-1
	UBE2T/FANCL-IN-1 is a highly effective inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation. It greatly enhances the sensitivity of cells to Carboplatin, a DNA cross-linking agent.
T19568	Sulfo-SMPB sodium		Others
	Sulfo-SMPB sodium is a non-cleavable heterobifunctional chemical cross-linking reagent that combines N-hydroxysuccinimide ester and maleimide groups. This compound enables the covalent conjugation of molecules possessing...		Others
T40642	Chlorpyrifos-oxon
	Chlorpyrifos-oxon, an active metabolite of Chlorpyrifos, is a powerful phosphorylating agent with potent inhibition of AChE activity. It induces cross-linking between tubulin subunits and disrupts microtubule function[4]...
TN4345	Jacobine		Others
	Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.		Others
T19203	Bendamustine D4	SDX-105 D4	Others
	Bendamustine D4 is the deuterium-labeled Bendamustine. Bendamustine is a DNA cross-linking compound with alkylating and antimetabolite properties. Bendamustine causes DNA breaks.		Others
T40947	PR-104 sodium
	PR-104 sodium is a hypoxia-activated DNA cross-linking agent used in the research of tumor xenograft models. It functions as a nitrogen mustard pre-prodrug and efficiently transforms into the more lipophilic dinitrobenza...
T19945	N,N'-Carbonyldiimidazole	1,1'-Carbonyldiimidazole,N,N'-Carbonyldiimidazole,CDI Crosslinker	Others
	N,N'-Carbonyldiimidazole is a biological cross-linking agent that has great application in mass spectrometry to detect the purity of compounds.		Others