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Search Results for " chimeric "

20

Compounds

Cat No. Product Name Synonyms Targets
T18893 5(6)-Carboxyfluorescein 5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM Others
5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid.
T77456 Lumiliximab IDEC-152,ST-152
Lumiliximab (IDEC-152) is a primate-ized chimeric antibody targeting CD23 rhesus monkey/human chimeric antibody with inhibitory effects on IgE antibody production for the study of allergic diseases.
T9910 Rituximab Others
Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM.
T76671 Amatuximab MORab-009 Others
Amatuximab (MORab-009) is a chimeric IgG1/k monoclonal antibody humanized against cell surface mesoleptin (MSLN) with antitumor activity for the treatment of solid tumors.
T22889 KF38789 KF 38789 Others
KF38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.
T76718 Brentuximab TNF
Brentuximab is a chimeric antibody targeting CD30 and is a naked antibody to Brentuximab vedotin.Brentuximab has antitumor activity and may be used to study relapsed or refractory Hodgkin's lymphoma.
T76773 Rolinsatamab IL Receptor
Rolinsatamab is a fully humanized selective monoclonal antibody that is a potent dual inhibitor of IL-4 and IL-13. Rolinsatamab chimeric antigen receptor sequence T cells. Rolinsatamab can be used to prevent and treat im...
T73698 Basiliximab CHI 621 Interleukin
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive activity and can be used in the study of kidney transplantat...
T76844 Abciximab C7E3 Integrin
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa...
TP1991L M 1145 acetate Neuropeptide Y Receptor
M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher af...
T76830 Teneliximab Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819 TNF
Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD...
T77484 Atibuclimab TNF
Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region. Atibuclimab can be used to treat amyotrophic lateral sclerosis. Atibuclimab reduces LPS-indu...
T39954 AU-15330 Epigenetic Reader Domain , PROTACs
AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergisticall...
T31949 Glutathione amide GASH cpd,L-gamma-Glutamyl-L-cysteinylglycinamide
Glutathione amide is a enzyme of a chimeric protein.
T34858 THIQ-20c THIQ 20c
THIQ-20c is a steroidomimetic and chimeric microtubule disruptor.
T39364 Desthiobiotin-PEG4-propargyl Desthiobiotin-PEG4-propargyl
Desthiobiotin-PEG4-propargyl is a PEG-coupled PROteolysis TArgeting Chimeric (PROTAC) linker, employed for PROTAC synthesis.
T15517 Hydroxy-PEG2-C2-PFP ester Others
Hydroxy-PEG2-C2-PFP ester, a PEG/Alkyl/ether-based PROteolysis TArgeting Chimeric (PROTAC) linker, is suitable for the synthesis of PROTACs.
T15512 Hydroxy-PEG1-(CH2)2-Boc Others
Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].
T17458 Azide-PEG-amine (MW 3500) Others
Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) derived linker compound, specifically designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].
T16190 N-(Azido-PEG3)-N-Boc-PEG4-Boc Others
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimeric (PROTAC) linker employed in PROTAC synthesis[1].
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TargetMol