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Search Results for " antiallodynic "

7

Compounds

Cat No. Product Name Synonyms Targets
T60003 AC1-IN-1 Adenylyl cyclase
AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
T0437 Inosine INO 495,NSC 20262 ROS , Endogenous Metabolite , Adenosine Receptor
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.
T27405 GAT211 GAT-211,AZ-4,GAT 211,AZ 4,AZ4
GAT211 is a CB1 positive allosteric modulator. GAT211 suppresses allodynia and produces synergistic antiallodynic effects with monoacylglycerol lipase and fatty acid amide hydrolase inhibitors in paclitaxel-treated mice.
T3699 Bay 59-3074 Cannabinoid Receptor
Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM). In rat models of chronic neuropathic and inflammatory pain, it displays anti-hyperalgesic and antiallodynic properties.
TN4660 Niranthin Anti-infection , HBV , PAFR , Topoisomerase
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N...
T17006 TC-I 2014 TRP/TRPV Channel
TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine,...
T78915 AD186 Sigma receptor
AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R. Notably, AD186 completely reverses the antiallodynic effect of BD-1063 [1].
TargetMol