anti-hyperlipidemic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
TN1438	Beta-Amyrin acetate		Antioxidant , HMG-CoA Reductase , Epoxide Hydrolase , Antifungal
	beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
T24865	Tenivastatin	L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid	ROS , HMG-CoA Reductase
	Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia.		ROS , HMG-CoA Reductase
T0254	Probucol	DH-581	Virus Protease , ABC , Lipid
	Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.		Virus Protease , ABC , Lipid
T4179	Probucol disuccinate		LDL
	Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.		LDL
T5S0662	Gelsemine	Gelsemin	Antioxidant
	1. Gelsemine (Gelsemin) has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cance...		Antioxidant
TN1097	β-Boswellic acid	Beta-boswellic acid	Lipoxygenase , DNA/RNA Synthesis
	β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.		Lipoxygenase , DNA/RNA Synthesis
T7529	Yamogenin		Others
	Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.		Others
T61430	S-2E
	S-2E is a compound that functions as an orally active, noncompetitive inhibitor of both HMG-CoA reductase and acetyl-CoA carboxylase. It exhibits an anti-hyperlipidemic action, making it suitable for studying conditions ...
T83562	(2R)-Flavanomarein
	'(2R)-Flavanomarein, a major flavonoid from Coreopsis tinctoria Nutt, exhibits protective effects against diabetic nephropathy and possesses antioxidative, antidiabetic, antihypertensive, and anti-hyperlipidemic properti...