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Search Results for " anti-depression "

15

Compounds

Cat No. Product Name Synonyms Targets
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T9272 Xaliproden hydrochloride Dopamine Receptor , 5-HT Receptor
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T2371 Emapunil AC-5216,XBD-173 Others
Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
T21233 Dihydrolipoic acid Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid Antioxidant
Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydr...
T67937 Ampreloxetine hydrochloride TD-9855 HCl
Ampreloxetine hydrochloride (TD-9855 HCl) has anti-inflammatory activity and is a potential compound for the treatment of depression and Alzheimer's disease.
T10201 PDE IV-IN-1 PDE
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound...
T50003 Debrisoquin hydriodide 1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide Others
Debrisoquin hydriodide (1,2,3,4-tetrahydroisoquinoline-2-carboximidamide hydroiodide) has antioxidant, anti-inflammatory and neuroprotective properties. It has also been found to modulate the activity of certain neurotra...
TN1015 Meranzin Adrenergic Receptor , Immunology/Inflammation related
Meranzin, a bioactive compound derived from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS) and isolated from Murraya exotica L. leaves, targets the alpha 2-adrenoceptor and engages the AMPA-ERK1/2–BDNF si...
T32535 Ladostigil TV-3326,Ladostigil,TV 3326,TV3326,Ladostigil free base Antioxidant , MAO , AChE
Ladostigil (Ladostigil free base) is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with inhibitory effects on MAO-B and AChE, with IC50 values of 37.1 and 31.8 μM, respecti...
T61625 GABAA receptor agonist 2
GABAA receptor agonist 2 (compound 4c) is a highly potent GABAA receptor agonist which exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding ...
T60842 GABAA receptor agonist 1
GABAA receptor agonist 1 (compound 3e) is a potent agonist of GABAA receptor that binds at the GABA binding site of GABAA receptor to produce GABAergic effects. GABAA receptor agonist 1 has anti-depression activities in ...
T39513 Ladostigil hemitartrate TV-3326 hemitartrate,Ladostigil hemitartrate
Ladostigil hemitartrate (TV-3326) is a compound that acts as a dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO). It has IC50 values of 37.1 μM for MAO-B and 31.8 μM for AChE. In addition, Lado...
TN4519 Mesuaxanthone A Others
Mesuaxanthone A and mesuaxanthone B are two yellow pigments.They produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of ...
TN1194 16beta,17-Dihydroxy-ent-kaurane-19-oic acid HIV Protease
16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50 value of 0.8 microgram/mL. It also possesses the activities...
T72247 Ladostigil hydrochloride TV-3326 hydrochloride
Ladostigil hydrochloride (TV-3326), an orally active compound, acts as a dual inhibitor targeting both cholinesterase and brain-selective monoamine oxidase (MAO), demonstrating inhibition constants (IC50s) of 31.8 μM for...
TargetMol