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PDE IV-IN-1

🥰Excellent
Catalog No. T10201Cas No. 225100-12-9

PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.

PDE IV-IN-1

PDE IV-IN-1

🥰Excellent
Purity: 99.79%
Catalog No. T10201Cas No. 225100-12-9
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.
Pack SizePriceAvailabilityQuantity
1 mg$251In Stock
5 mg$533In Stock
10 mg$713In Stock
25 mg$1,070In Stock
50 mg$1,430In Stock
100 mg$1,930In Stock
200 mg$2,590In Stock
1 mL x 10 mM (in DMSO)$601In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.79%
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Product Introduction

Bioactivity
Description
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.
Chemical Properties
Molecular Weight386.88
FormulaC20H23ClN4O2
Cas No.225100-12-9
SmilesC(N1C=2C(N=C1C)=C(C)N=C(Cl)N2)C3=CC(OC4CCCC4)=C(OC)C=C3
Relative Density.1.35 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (142.16 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5848 mL12.9239 mL25.8478 mL129.2390 mL
5 mM0.5170 mL2.5848 mL5.1696 mL25.8478 mL
10 mM0.2585 mL1.2924 mL2.5848 mL12.9239 mL
20 mM0.1292 mL0.6462 mL1.2924 mL6.4620 mL
50 mM0.0517 mL0.2585 mL0.5170 mL2.5848 mL
100 mM0.0258 mL0.1292 mL0.2585 mL1.2924 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

phosphodiesterase 4PDE IV-IN-1PDE IVIN1PDE IV IN 1
Related Tags: buy PDE IV-IN-1 | purchase PDE IV-IN-1 | PDE IV-IN-1 cost | order PDE IV-IN-1 | PDE IV-IN-1 chemical structure | PDE IV-IN-1 formula | PDE IV-IN-1 molecular weight
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