anti-depressant — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0692	Allopurinol	Zyloric,Zyloprim,Lopurin	ROS , Xanthine Oxidase
	Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.		ROS , Xanthine Oxidase
T6376	Allopurinol Sodium	Allopurinol sodium salt,Sodium allopurinol	ROS
	Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.		ROS
T23394	SR 57227A	SR 57227 hydrochloride	5-HT Receptor
	SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier. It has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 rece...		5-HT Receptor
T15812	LY2979165	mGlu2 agonist	GluR
	LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.		GluR
T11097	Drobuline hydrochloride		Others
	Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant activity.		Others
T4S1519	Pseudoginsenoside RT5		Others
	1. Pseudoginsenoside RT5 has anti-epilepsy, anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor and anti-malaria activities.		Others
T0235	Modaline sulfate		MAO , Monoamine Oxidase
	Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by t...		MAO , Monoamine Oxidase
T6649	(S)-(+)-Rolipram	(S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram	Apoptosis , PDE
	(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.		Apoptosis , PDE
T9846	5-HT3 antagonist 5
	5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound which is a 5-HT 3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT 3 agonist and 2-methyl-5-HT, and exhibits anti-depressant effect in mice [1].
T1320	Disopyramide	Triombrin,Hypaque sodium,amidotrizoate sodium	Potassium Channel , Sodium Channel , AChR
	Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the h...		Potassium Channel , Sodium Channel , AChR
T25344	Disobutamide
	Disobutamide is used as a Cardiac Depressant (Anti-Arrhythmic).
T28850	SR57227A	SR 57227A,SR-57227A
	SR 57227A is a highly selective of peripheral and central 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreas...
T70021	Oleanolic acid acrylate
	Oleanolic acid acrylate (OAA) is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A and a derivative of oleanolic acid. It is also a selective inhibitor of MAO-A with anti-depressant-like and anxiolytic activitie...
T73273	SERT-IN-2
	SERT-IN-2, a potent SERT inhibitor (IC 50 = 0.58 nM), exhibits promising efficacy as an anti-depressant. It demonstrates a favorable bioavailability of 83.28% in rats and has the ability to cross the blood-brain barrier.