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Search Results for " alkylating "

20

Compounds

Cat No. Product Name Synonyms Targets
T8897 2-Iodoacetamide Iodoacetamide Others
Iodoacetamide, an alkylating agent, is commonly utilized for cysteine alkylation in proteomics sample preparation.
T8380 Bendamustine SDX105 Apoptosis , Others , DNA Alkylator/Crosslinker
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
T4169 N-Nitroso-N-methylurea 1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea Others , DNA Alkylator/Crosslinker
N-Nitroso-N-methylurea (Methylnitrosourea) is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
T0095 Bendamustine hydrochloride SDX-105,SDX-105 (Cytostasane) HCl,Bendamustine HCl,EP-3101 Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
T26978 CEP-40125 RXDX-107 DNA Alkylation
CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.
T1241 Altretamine Hexamethylmelamine,NSC13875,RB-1515,ENT-50852,WR-95704 DNA Alkylator/Crosslinker , DNA Alkylation
Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.
T19736 Aniline mustard Mesylerythrol,NSC-18429,Lymphocin Others
Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.
T13689 Ethylene dimethanesulfonate Apoptosis
Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. 
T1250 Thio-TEPA Tiofosyl,Triethylenethiophosphoramide,Tiofosfamid DNA Alkylator/Crosslinker , DNA Alkylation , Antibacterial , Antibiotic
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
T3091 Carmustine bis-chloroethylnitrosourea,Nitrumon,Gliadel,BCNU,BiCNU,Carmubris DNA Alkylator/Crosslinker , DNA Alkylation
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.
T0707L Cyclophosphamide DNA Alkylator/Crosslinker , DNA , MRP
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T1601 Lomustine CCNU,NSC 79037 Apoptosis , Others , DNA Alkylator/Crosslinker , DNA Alkylation , Autophagy
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.
T17159 Treosulfan NSC 39069,Treosulphan DNA Alkylator/Crosslinker , DNA Alkylation
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
T17212 VAL-083 Dianhydrogalactitol,Dianhydrodulcitol DNA Alkylator/Crosslinker , DNA Alkylation
VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
T16871 Semustine DNA Alkylator/Crosslinker
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.
T0707 Cyclophosphamide hydrate Cyclophosphamide monohydrate DNA Alkylator/Crosslinker , DNA , MRP
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities.
T28663 Sarmustine NSC-364432,SarCNU,Sarcosinamide,NSC 364432,NSC364432
Sarmustine (SarCNU) is an alkylating agent with anticancer activity that inhibits the growth of prostate cancer cells via p53-dependent and p53-independent pathways.Sarmustine mediates the selection of P140K methylguanin...
T1178 Temozolomide NSC 362856,TZM,CCRG 81045,TMZ Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy.
T21463 Temozolomide Acid TMZA Others
Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocyt...
T0164 Oxaliplatin L-OHP DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop...

Compounds

2-Iodoacetamide
T8897
Synonym: Iodoacetamide
Target: Others
Bendamustine
T8380
Synonym: SDX105
Target: Apoptosis, Others, DNA Alkylator/Crosslinker
N-Nitroso-N-methylurea
T4169
Synonym: 1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea
Target: Others, DNA Alkylator/Crosslinker
Bendamustine hydrochloride
T0095
Synonym: SDX-105,SDX-105 (Cytostasane) HCl,Bendamustine HCl,EP-3101
Target: Apoptosis, DNA Alkylator/Crosslinker, DNA/RNA Synthesis
CEP-40125
T26978
Synonym: RXDX-107
Target: DNA Alkylation
Altretamine
T1241
Synonym: Hexamethylmelamine,NSC13875,RB-1515,ENT-50852,WR-95704
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Aniline mustard
T19736
Synonym: Mesylerythrol,NSC-18429,Lymphocin
Target: Others
Ethylene dimethanesulfonate
T13689
Synonym:
Target: Apoptosis
Thio-TEPA
T1250
Synonym: Tiofosyl,Triethylenethiophosphoramide,Tiofosfamid
Target: DNA Alkylator/Crosslinker, DNA Alkylation, Antibacterial, Antibiotic
Carmustine
T3091
Synonym: bis-chloroethylnitrosourea,Nitrumon,Gliadel,BCNU,BiCNU,Carmubris
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Cyclophosphamide
T0707L
Synonym:
Target: DNA Alkylator/Crosslinker, DNA, MRP
Lomustine
T1601
Synonym: CCNU,NSC 79037
Target: Apoptosis, Others, DNA Alkylator/Crosslinker, DNA Alkylation, Autophagy
Treosulfan
T17159
Synonym: NSC 39069,Treosulphan
Target: DNA Alkylator/Crosslinker, DNA Alkylation
VAL-083
T17212
Synonym: Dianhydrogalactitol,Dianhydrodulcitol
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Semustine
T16871
Synonym:
Target: DNA Alkylator/Crosslinker
Cyclophosphamide hydrate
T0707
Synonym: Cyclophosphamide monohydrate
Target: DNA Alkylator/Crosslinker, DNA, MRP
Sarmustine
T28663
Synonym: NSC-364432,SarCNU,Sarcosinamide,NSC 364432,NSC364432
Target:
Temozolomide
T1178
Synonym: NSC 362856,TZM,CCRG 81045,TMZ
Target: Apoptosis, DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
Temozolomide Acid
T21463
Synonym: TMZA
Target: Others
Oxaliplatin
T0164
Synonym: L-OHP
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
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TargetMol