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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8897 | 2-Iodoacetamide | Iodoacetamide | Others |
Iodoacetamide, an alkylating agent, is commonly utilized for cysteine alkylation in proteomics sample preparation. | |||
T8380 | Bendamustine | SDX105 | Apoptosis , Others , DNA Alkylator/Crosslinker |
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia | |||
T4169 | N-Nitroso-N-methylurea | 1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea | Others , DNA Alkylator/Crosslinker |
N-Nitroso-N-methylurea (Methylnitrosourea) is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties. | |||
T0095 | Bendamustine hydrochloride | SDX-105,SDX-105 (Cytostasane) HCl,Bendamustine HCl,EP-3101 | Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis |
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage. | |||
T26978 | CEP-40125 | RXDX-107 | DNA Alkylation |
CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors. | |||
T1241 | Altretamine | Hexamethylmelamine,NSC13875,RB-1515,ENT-50852,WR-95704 | DNA Alkylator/Crosslinker , DNA Alkylation |
Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity. | |||
T19736 | Aniline mustard | Mesylerythrol,NSC-18429,Lymphocin | Others |
Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity. | |||
T13689 | Ethylene dimethanesulfonate | Apoptosis | |
Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. | |||
T1250 | Thio-TEPA | Tiofosyl,Triethylenethiophosphoramide,Tiofosfamid | DNA Alkylator/Crosslinker , DNA Alkylation , Antibacterial , Antibiotic |
Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity. | |||
T3091 | Carmustine | bis-chloroethylnitrosourea,Nitrumon,Gliadel,BCNU,BiCNU,Carmubris | DNA Alkylator/Crosslinker , DNA Alkylation |
Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent. | |||
T0707L | Cyclophosphamide | DNA Alkylator/Crosslinker , DNA , MRP | |
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer. | |||
T1601 | Lomustine | CCNU,NSC 79037 | Apoptosis , Others , DNA Alkylator/Crosslinker , DNA Alkylation , Autophagy |
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors. | |||
T17159 | Treosulfan | NSC 39069,Treosulphan | DNA Alkylator/Crosslinker , DNA Alkylation |
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types. | |||
T17212 | VAL-083 | Dianhydrogalactitol,Dianhydrodulcitol | DNA Alkylator/Crosslinker , DNA Alkylation |
VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity. | |||
T16871 | Semustine | DNA Alkylator/Crosslinker | |
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia. | |||
T0707 | Cyclophosphamide hydrate | Cyclophosphamide monohydrate | DNA Alkylator/Crosslinker , DNA , MRP |
Cyclophosphamide hydrate is a DNA alkylating agent, an inhibitor of DNA synthesis. Cyclophosphamide hydrate has antitumor and immunosuppressive activities. | |||
T28663 | Sarmustine | NSC-364432,SarCNU,Sarcosinamide,NSC 364432,NSC364432 | |
Sarmustine (SarCNU) is an alkylating agent with anticancer activity that inhibits the growth of prostate cancer cells via p53-dependent and p53-independent pathways.Sarmustine mediates the selection of P140K methylguanin... | |||
T1178 | Temozolomide | NSC 362856,TZM,CCRG 81045,TMZ | Apoptosis , DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy |
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. | |||
T21463 | Temozolomide Acid | TMZA | Others |
Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocyt... | |||
T0164 | Oxaliplatin | L-OHP | DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy |
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop... |