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Thio-TEPA

Name: Thio-TEPA
Brand: TargetMol
SKU: T1250
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1250Cas No. 52-24-4

Alias Triethylenethiophosphoramide, Tiofosyl, Tiofosfamid

Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.

Thio-TEPA

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Purity: 99.07%

Catalog No. T1250Alias Triethylenethiophosphoramide, Tiofosyl, TiofosfamidCas No. 52-24-4

Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.

Pack Size	Price	Availability
5 mg	$31	In Stock
10 mg	$44	In Stock
25 mg	$72	In Stock
50 mg	$113	In Stock
100 mg	$189	In Stock
200 mg	$278	In Stock
500 mg	$475	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

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Batch Information

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Purity:99.07%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
Synonyms	Triethylenethiophosphoramide, Tiofosyl, Tiofosfamid

Chemical Properties

Molecular Weight	189.22
Formula	C₆H₁₂N₃PS
Cas No.	52-24-4
Smiles	P(=S)(N1CC1)(N2CC2)N3CC3
Relative Density.	1.5g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 91 mg/mL (480.92 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.2849 mL	26.4243 mL	52.8485 mL	264.2427 mL
5 mM	1.0570 mL	5.2849 mL	10.5697 mL	52.8485 mL
10 mM	0.5285 mL	2.6424 mL	5.2849 mL	26.4243 mL
20 mM	0.2642 mL	1.3212 mL	2.6424 mL	13.2121 mL
50 mM	0.1057 mL	0.5285 mL	1.0570 mL	5.2849 mL
100 mM	0.0528 mL	0.2642 mL	0.5285 mL	2.6424 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc