Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 43.00 | |
50 mg | In stock | $ 70.00 | |
100 mg | In stock | $ 126.00 | |
200 mg | In stock | $ 216.00 | |
500 mg | In stock | $ 362.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage. |
Targets&IC50 | DNA damage:50 μM |
Cell Research | SU-DHL-1 and SU-DHL-9 cells are preincubated for 30 minutes with either 6 mM methoxyamine or 50 μM O6-benzylguanine, inhibitors of Ape-1 base excision repair enzyme, or alkylguanyl transferase enzyme, respectively. The cells are then exposed to various concentrations of Bendamustine for 72 hours. Cytotoxicity is evaluated by the MTT viability assay and an IC50 is determined as the drug concentration that inhibited by 50% the viability value of the untreated control. Analyses are done.(Only for Reference) |
Synonyms | SDX-105, SDX-105 (Cytostasane) HCl, Bendamustine HCl, EP-3101 |
Molecular Weight | 394.72 |
Formula | C16H21Cl2N3O2·HCl |
CAS No. | 3543-75-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 14 mg/mL (35.5 mM)
H2O: 2 mg/mL (5.06 mM)
DMSO: 72 mg/mL (182.4 mM)
You can also refer to dose conversion for different animals. More
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Bendamustine hydrochloride 3543-75-7 Apoptosis Cell Cycle/Checkpoint DNA Damage/DNA Repair DNA Alkylator/Crosslinker DNA/RNA Synthesis EP 3101 EP3101 SDX-105 SDX-105 (Cytostasane) HCl antimetabolite alkylating purine anticancer inhibit SDX 105 Inhibitor Bendamustine HCl Bendamustine Bendamustine Hydrochloride EP-3101 DNA SDX105 inhibitor