visceral — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12137	N-(2-Hydroxypropyl)methacrylamide		Parasite
	N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.		Parasite
T5491	GSK3179106		c-RET
	GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM		c-RET
T2525	Alosetron hydrochloride	Lotronex,GR 68755C,GR 68755,GR 68755X	5-HT Receptor
	Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system,...		5-HT Receptor
T39746	DNDI-6148
	DNDI-6148 is a novel preclinical candidate for the treatment of visceral leishmaniasis.
T0033	Miltefosine	HePC,Hexadecyl phosphocholine	Akt , HIV Protease , PKC
	Miltefosine (HePC) is the treatment of visceral and cutaneous leishmaniasis drug , and is proceeding clinical trials for this in several countries. Several medical agents produce some potency against visceral or cutaneou...		Akt , HIV Protease , PKC
T20225	Dicentrine, (-)-	L-Dicentrine,NSC 251699,NSC251699,NSC-251699	Others
	Dicentrine, (-)- (NSC-251699) is an aporphinic alkaloid found in several plant species, which showed significant antinociceptive activity in an acute model of visceral pain in mice.		Others
T33846	Oxyphenonium bromide	Spasmophen,Oxifenon,Oxyfenon,Atrenyl,Oxyphenon	Others
	Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms.		Others
TN6791	Palvanil	Hexadecanamide	TRP/TRPV Channel
	Palvanil (Hexadecanamide) is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.		TRP/TRPV Channel
T37427	(2R/S)-6-PNG	6-Prenylnaringenin,(±)-6-Prenylnaringenin	Calcium Channel , HDAC
	(2R/S)-6-PNG (6-Prenylnaringenin) is a novel natural histone deacetylase inhibitor with anticancer and antitumor activity, and blocks T-type calcium channels to reduce neuropathic and visceral pain in mice.		Calcium Channel , HDAC
T7295	Miridesap	Ro63-8695,CPHPC,GSK2315698	Others
	Miridesap (GSK2315698) is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fluid and visceral amyloid de...		Others
T16448	PD173212		Calcium Channel
	PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently reduced DNBS-induced visceral hypersensitivity in mice.		Calcium Channel
TP1057L	Phe-Met-Arg-Phe Like Peptide acetate	Pqdpflrfamide acetate,Phe-Met-Arg-Phe Like Peptide acetate（98495-35-3 free base)	Others
	Phe-Met-Arg-Phe Like Peptide acetate (Pqdpflrfamide acetate) is a FMRF-like peptide from visceral and somatic muscles of the snail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide consisting of 4 amino aci...		Others
T39214L	LXE408 fumarate	LXE408 fumarate (1799330-15-6 Free base)	Proteasome
	LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. LXE408 fuma...		Proteasome
T2P2923	Stearic acid	Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase , Endogenous Metabolite
	1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have...		Phosphatase , Endogenous Metabolite
T71716	Nav1.1-IN-B
	Nav1.1-IN-B is a selective NaV1.1 inhibitor which reduces visceral hypersensitivity.
T71308	DSP-6952
	DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.
T12970L	Solabegron HCl	GW-427,353,GW427353,GW-427353,GW 427,353,GW427,353
	Solabegron (GW-427,353), is a selective agonist of β3 adrenergic receptors. In addition, Solabegron has been shown to produce visceral analgesia by releasing somatostatin from fat cells.
T28346	PD-217014 HCl	PD 217014,PD217014,PD-217,014,PD-217014
	PD-217014 is a GABA analog. It inhibits (3)H-gabapentin binding to alpha(2)delta subunit of voltage-gated calcium channels in a concentration-dependent manner (K(i) = 18 nmol/l). PD-217014 possesses visceral analgesic ac...
T33637	Neostibosan	Stibanilic acid,693B,Astaril,Ethylstibamine,p-Aminobenzenestibonic acid,Bayer 693
	Neostibosan is an arsenic-containing parasitic agent. Due to the activity of arsenic on visceral L/Ashmaniasis, one of the pentvalent antimony, which is less toxic, is synthesized and has potential activity on tumor cell...
TP1057	Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa	Phe-Met-Arg-Phe Like Peptide
	Phe-Met-Arg-Phe-like peptide, derived from the visceral and somatic muscles of the snail Helix aspersa, is a neuropeptide known as FMRF (Phe-Met-Arg-Phe). This peptide comprises four amino acid residues[1].