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Neostibosan

Catalog No. T33637 CAS 554-76-7

Synonyms: Stibanilic acid, 693B, Astaril, Ethylstibamine, p-Aminobenzenestibonic acid, Bayer 693

Neostibosan is an arsenic-containing parasitic agent. Due to the activity of arsenic on visceral L/Ashmaniasis, one of the pentvalent antimony, which is less toxic, is synthesized and has potential activity on tumor cells.

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Neostibosan, CAS 554-76-7

Pack Size	Availability	Price/USD	Quantity
25 mg	6-8 weeks	$ 1,520.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Stibanilic acid, 693B, Astaril, Ethylstibamine, p-Aminobenzenestibonic acid, Bayer 693
Molecular Weight	263.89
Formula	C6H8NO3Sb
CAS No.	554-76-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Hadjikakou SK, Ozturk II, Banti CN, Kourkoumelis N, Hadjiliadis N. Recent advances on antimony(III/V) compounds with potential activity against tumor cells. J Inorg Biochem. 2015 Dec;153:293-305. doi: 10.1016/j.jinorgbio.2015.06.006. Epub 2015 Jun 10. Review. PubMed PMID: 26092367. 2. Cambronero Galache M, Martínez Cortés F, Bódalo Herrero A, Courel Grijalba A, Casado Flores J, Casquero Junquera J. [Kala-azar in childhood. 20 year review]. An Esp Pediatr. 1983 Jan;18(1):28-32. Spanish. PubMed PMID: 6870075. 3. Duke BO. The effects of drugs on Onchocerca volvulus. 2. The antimonial preparations TWSb and MSbE. Bull World Health Organ. 1968;39(2):147-55. PubMed PMID: 4881067; PubMed Central PMCID: PMC2554559. 4. IVADY G, FRIEDRICH E. [Comparative studies on the efficacy of pentamidine, Solustibosan and Neostibosan against Candida albicans]. Dtsch Gesundheitsw. 1960 Oct 27;15:2130-2. German. PubMed PMID: 13718206.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Neostibosan 554-76-7 Stibanilic acid 693B Astaril Ethylstibamine p-Aminobenzenestibonic acid Bayer 693 inhibitor inhibit

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