tandem — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T26249	TANDEM (quinoxaline)	Tandem
	TANDEM (quinoxaline) is a synthetic analog of antibiotics quinoxaline.
T19340	Glutarylcarnitine	O-glutaroyl-L-carnitine	Endogenous Metabolite
	Glutarylcarnitine (O-glutaroyl-L-carnitine) is a diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.		Endogenous Metabolite
T8873	Bractoppin		Others , DNA/RNA Synthesis
	Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...		Others , DNA/RNA Synthesis
T2S0265	Robinin	NSC 9222	TLR
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR...		TLR
T9742	SETDB1-TTD-IN-1		Histone Methyltransferase
	SETDB1-TTD-IN-1 is a potent, selective and endogenous binder competitive inhibitor of SETDB1-TTD with a Kd of 88 nM.		Histone Methyltransferase
T9428	HM43239		FLT
	HM43239 is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. HM43239 directly inhibits the k...		FLT
T37514	Hydroxy Dimetridazole		Drug Metabolite
	Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected t...		Drug Metabolite
T73752	Glutarylcarnitine lithium
	Glutarylcarnitine lithium, a key diagnostic metabolite for malonic aciduria and glutaric aciduria type I, is routinely monitored in the majority of newborn screening programs utilizing tandem mass spectrometry [1].
T19236	Cholesteryl behenate	Cholesteryl docosanoate,Cholesterol behenate	Others
	Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol.		Others
T39754	HKPerox-2
	HKPerox-2 is an excellently selective and sensitive green fluorescent probe toward H 2 O 2 over 30-fold other tested ROS/RNS in chemical and biological systems. HKPerox-2 is a O-methyl rhodol derivative and specifically ...
T39818	Desmorpholinyl Quizartinib-PEG2-COOH	Desmorpholinyl Quizartinib-PEG2-COOH
	Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal ta...
T80858	Vixtimotamab	TandAb T564,AMV-564
	Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively engages human CD33 and CD3 antigens. It is utilized in research on acute myeloid leukemia (AML) [1].
T19385	ITIC-4F		CXCR
	ITIC-4F, an indacenodithienothiophene (IDTT)-based postfullerene electron acceptor, exhibits wide applicability in high-efficiency binary and ternary single-junction as well as tandem polymer solar cells (PSCs).		CXCR
T62863	FLT3/ITD-IN-4
	FLT3/ITD-IN-4 (Compound 16) is a selective inhibitor of FLT3 internal tandem repeat mutations (FLT3-ITD) (IC50: 2.3 nM). FLT3/ITD-IN-4 can be used to study acute myeloid leukaemia.
T12555	PROTAC FLT-3 degrader 1		Others , PROTACs
	PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.		Others , PROTACs
T36128	Tolmetin β-D-Glucuronide
	Tolmetin β-D-Glucuronide has reactive properties with human serum albumin, allowing identification of the binding site and reaction mechanism by tandem mass spectrometry.
T61415	FLT3/ITD-IN-1
	FLT3/ITD-IN-1 (Compound 1) is a highly potent inhibitor of FLT3 internal tandem duplications (FLT3-ITD). It exhibits remarkable inhibitory effects against FLT3 and FLT3-ITD, with impressive IC50 values of 38.2 nM and 144...
T12271	NV03		Others
	NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 is a possible application as...		Others
T37209	5-hydroxy Flunixin
	5-hydroxy Flunixin is a metabolite of the COX inhibitor flunixin .1 1.Daeseleire, E., Mortier, L., De Ruyck, H., et al.Determination of flunixin and ketoprofen in milk by liquid chromatography-tandem mass spectrometryAna...
T36681	Sorafenib N-oxide
	Sorafenib N-oxide is an active metabolite of sorafenib , an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD; Kd =...